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Titre : | An Analysis of Weight Gains and Body Mass Index in Patients with Barretts Esophagus (2016) |
Type de document : | Article |
Dans : | Journal of the academy of nutrition and dietetics (vol 116, n° 7, 2016) |
Article en page(s) : | 1156-1161 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Oesophage de Barrett ; Prise de poids ; Reflux gastro-oesophagien ; Régime alimentaire |
Résumé : |
Background
Obesity is a risk factor for developing Barretts esophagus (BE), a precursor to esophageal cancer. Long BE lengths are associated with greater risk for malignancy. How weight gains from young adulthood (defined as ages 19 to 29 years) affect BE length is unknown. Objective To examine current body mass index (BMI), weight gains from young adulthood, and evening snacking near bedtime during young adulthood in BE patients. Design Cross-sectional analysis of 71 patients from 2001 to 2008 from a 600-bed tertiary care center in the United States who were newly diagnosed with BE by endoscopy and mucosal biopsies. Main outcome measures Barretts esophagus length and age at presentation. Statistical analyses performed Pearsons correlation coefficient (r) measured the linear association between continuous variables. The Kruskal-Wallis test was used to compare medians by segment length and the chi-squared test or Fishers exact test for categorical data. Quantile regression was used for multivariable adjustment. Results Younger patients had higher BMIs at diagnosis (r=-0.32, P=0.007). Patients who gained more than 23 kg from young adulthood were diagnosed at an adjusted median age of 18.0 years younger 95% CI (6.1-29.9, P=0.004) than patients with no weight gains. BMI was not correlated with BE length (r=-0.12, P=0.33). Weight gains from young adulthood were not associated with BE length after multivariable adjustment (P=0.19). Patients whose late evening snack or bedtime was less than 4 hours from dinner had longer median BE lengths than those who went to bed later (5 vs 2 cm, P=0.02). Conclusions Longer BE lengths were associated with shorter dinnerbedtime intervals during young adulthood but not with current BMI or weight gains from young adulthood. |
Disponible en ligne : | Non |
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