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Titre : | A comparison of dioctahedral smectite and iodine glycerin cream with topical mouth rinse in treatment of chemotherapy induced oral mucositis : A pilot study (2015) |
Auteurs : | Jin-Xiang Lin, Auteur ; Zu-Yan Fan, Auteur ; Qu Lin, Auteur ; et al., Auteur |
Type de document : | Article |
Dans : | European Journal of Oncology Nursing (Vol. 19, n° 2, April 2015) |
Article en page(s) : | p. 136-141 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Chimiothérapie ; Hygiène ; Mucite ; Muqueuse de la bouche ; Oncologie médicale ; Soins ; Thérapeutique |
Résumé : |
Purpose of the research
To compare the efficacy of dioctahedral smectite and iodine glycerin (DSIG) cream with topical mouth rinse (composed of saline, gentamicin and Vitamin B12) in treatment of chemotherapy induced oral mucositis (OM). Methods and sample A total of 130 intensive chemotherapy or stem cells transplantation induced OM patients were recruited. Among these patients, 67 patients received topical mouth rinse and 63 patients received DSIG cream treatment. The OM would be treated on the OM appearance and sustained for 5 days. OM severity was measured daily using The American Oncology Nursing Society recommended Oral Assessment Guideline (OAG) score system. Key results Compared with topical mouth rinse treatment, a significant lower OAG score was observed in DSIG cream treated patients. Specifically, the OAG scores were respectively 12.1 ± 1.1, 12.0 ± 1.2, 11.3 ± 1.3 and 10.4 ± 1.3 from day 2 to day 5 in topical mouth rinse treatment subgroup. Correspondingly, the OAG scores were respectively 10.2 ± 1.0, 9.3 ± 0.9, 8.5 ± 0.6 and 8.0 ± 0.2 for DSIG cream treatment subset (all P Conclusions Compared with topical mouth rinse, DSIG cream significantly lowered the OAG score and shortened OM duration. |
Disponible en ligne : | Non |
Exemplaires (1)
Cote | Support | Localisation | Section | Disponibilité |
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REV | Périodique papier | Woluwe | Espace revues | Consultation sur place uniquement Exclu du prêt |