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Titre : | Gynecological malignancy risk in colorectal cancer survivors : A population-based cohort study (2015) |
Auteurs : | Wei-Chun Chang, Auteur ; Chih-Hsin Muo, Auteur ; Ji-An Liang, Auteur ; et al., Auteur |
Type de document : | Article |
Dans : | European Journal of Oncology Nursing (Vol. 19, n° 5, October 2015) |
Article en page(s) : | p. 473-478 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Assurance ; Gynécologie ; Survivants ; Tumeurs de l'ovaire ; Tumeurs du côlon ; Tumeurs du sein |
Résumé : |
Purpose
This study was carried out to assess the risk of gynecological malignancy in colorectal cancer survivors using a population-based retrospective cohort study. Method Using the National Health Insurance Research Database (NHIRD) of Taiwan, we identified 37,176 patients with colorectal cancer diagnosed in 19982009, aged 20 years and above, without other cancer history. We also randomly selected 148,700 women without any cancer in the comparison cohort, frequency matched by age and diagnosis date. Incidences and hazards of breast, cervix, endometrial and ovarian cancers were evaluated by 201l. Results The overall incidence of the 4 types of gynecological cancer was 39.0% higher in colorectal cancer patients than in comparisons (2.99 vs. 2.14 per 1000 person-years) with an adjusted hazard ratio (HR) of 1.46 (95% confidence interval (CI) = 1.311.62). Breast cancer accounted for most subsequent cancer. The multivariable Cox method measured HR was the highest for endometrial cancer (3.40, 95% CI = 2.594.47) for the colorectal cohort relative to comparisons, followed by ovarian cancer and breast cancer, except cervix cancer. The risk of gynecological malignancies was apparently elevated for colorectal cancer survivors Conclusions Follow-up measures are suggested for women with colorectal cancer for early detection and prevention of the subsequent gynecological malignancy. |
Disponible en ligne : | Non |
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Cote | Support | Localisation | Section | Disponibilité |
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REV | Périodique papier | Woluwe | Espace revues | Consultation sur place uniquement Exclu du prêt |