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Titre : | Effectiveness of exercise training on the dyspnoea of individuals with long COVID: A randomised controlled multicentre trial (2023) |
Auteurs : | Christophe Romanet ; Johan Wormser ; Audrey Fels ; Pauline Lucas ; Camille Prudat ; Emmanuelle Sacco ; Cédric Bruel ; Gaëtan Plantefève ; Frédéric Pene ; Gilles Chatellier ; François Philippart |
Type de document : | Article |
Dans : | Annals of Physical and Rehabilitation Medicine (Vol. 66, n° 5, June 2023) |
Article en page(s) : | 101765 |
Note générale : | https://doi.org/10.1016/j.rehab.2023.101765 |
Langues: | Anglais |
Descripteurs : |
HE Vinci COVID-19 ; Dyspnée ; Qualité de vie ; Réadaptation ; Syndrome de détresse respiratoire ; Syndrome post phase aiguë de la COVID-19 ; Techniques de physiothérapie |
Résumé : | Background COVID-19-related acute respiratory distress syndrome (CARDS) is a severe evolution of the Sars-Cov-2 infection and necessitates intensive care. COVID-19 may subsequently be associated with long COVID, whose symptoms can include persistent respiratory symptoms up to 1 year later. Rehabilitation is currently recommended by most guidelines for people with this condition. Objectives To evaluate the effects of exercise training rehabilitation (ETR) on dyspnoea and health-related quality of life measures in people with continuing respiratory discomfort following CARDS. Methods In this multicentre, two-arm, parallel, open, assessor-blinded, randomised controlled trial, we enroled adults previously admitted with CARDS to 3 French intensive care units who had been discharged at least 3 months earlier and who presented with an mMRC dyspnoea scale score > 1. Participants received either ETR or standard physiotherapy (SP) for 90 days. The primary outcome was dyspnoea, as measured by the Multidimensional Dyspnoea Profile (MDP), at day 0 (inclusion) and after 90 days of physiotherapy. Secondary outcomes were the mMRC and 12-item Short-Form Survey scores. Results Between August 7, 2020, and January 26, 2022, 487 participants with CARDS were screened for inclusion, of whom 60 were randomly assigned to receive either ETR (n = 27) or SP (n = 33). Mean MDP following ETR was 42% lower than after SP (26.15 vs. 44.76); a difference of -18.61 (95% CI -27.78 to -9.44; p |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/article/pii/S1877065723000362 |