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Titre : | Vagus Nerve Stimulation Paired With Upper-Limb Rehabilitation After Stroke: 2- and 3-Year Follow-up From the Pilot Study (2023) |
Auteurs : | Gerard E. Francisco ; Navzer D. Engineer ; Jesse Dawson ; Teresa J. Kimberley ; Steven C. Cramer ; Cecília N. Prudente ; David Pierce ; W. Brent Tarver ; Reema H. Adham Hinds ; Ann Van de Winckel ; Nuray Yozbatiran |
Type de document : | Article |
Dans : | Archives of Physical Medicine and Rehabilitation (Vol. 104, n° 8, 2023) |
Article en page(s) : | p. 1180-1187 |
Note générale : | https://doi.org/10.1016/j.apmr.2023.02.012 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Accident vasculaire cérébral (AVC) ; Activités de la vie quotidienne ; Membre supérieur ; Réadaptation ; Stimulation du nerf vague |
Résumé : | Objective To assess whether a long-term home-based intervention using Paired VNS therapy is feasible and whether the benefits of Paired VNS therapy are maintained beyond 1 year. Design A long-term follow-up study. Setting Three centers in the United States and 1 in the United Kingdom. Participants Adults with chronic ischemic stroke (n=15) with moderate to severe arm and hand impairment. Interventions Participants were implanted with a VNS device followed by 6 weeks of in-clinic therapy with Paired (Active) or control VNS followed by home-based rehabilitation through day 90 (blinded phase). The control VNS group then crossed over to receive 6 weeks of in-clinic Active VNS. Participants in both groups then continued a long-term home exercise program with self-administered Active VNS. Main Outcome Measures Fugl-Meyer Assessment for Upper Extremity (FMA-UE) and Wolf Motor Function Test (WMFT) Functional scores were evaluated at the end of in-clinic therapy and day 90. Since both groups were subsequently receiving home-based rehabilitation with Active VNS during the long term, follow-up outcome assessments were pooled for the analyses at 6, 9, and 12 months, as previously reported. Here, we report pooled analysis of outcomes beyond 1 year. Results |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/article/pii/S0003999323001478 |