| Titre : | Chocolate Consumption in Relation to All-Cause and Cause-Specific Mortality in Women: The Women's Health Initiative (2023) |
| Auteurs : | Yangbo Sun ; Buyun Liu ; Linda G. Snetselaar ; Robert B. Wallace ; Aladdin H. Shadyab ; Guo-Chong Chen ; James M. Shikany ; JoAnn E. Manson ; Wei Bao |
| Type de document : | Article |
| Dans : | Journal of the academy of nutrition and dietetics (Vol. 123, n° 6, June 2023) |
| Article en page(s) : | p. 902-911.e3 |
| Note générale : | https://doi.org/10.1016/j.jand.2022.12.007 |
| Langues: | Anglais |
| Descripteurs : |
HE Vinci Cause de décès ; Chocolat ; Démence ; Etudes prospectives ; Facteurs de risque ; Femmes ; Maladies cardiovasculaires ; Modèles des risques proportionnels ; Santé des femmes ; Tumeurs |
| Résumé : |
Background : Chocolate contains both potentially harmful components (ie, stearic acid and added sugar) and beneficial components (ie, phenolics and flavonoids). Despite its popularity, the long-term health effects of chocolate consumption remain unclear.
Objective : The aim of this study was to examine the association of chocolate consumption with all-cause and cause-specific mortality. Design : This was a prospective cohort study. Participants/setting : This study included 84,709 postmenopausal women free of cardiovascular disease (CVD) and cancer at baseline in the observational study and clinical trials control arms of the prospective Women's Health Initiative cohort who were enrolled during 1993 through 1998. These women were followed through March 2018. Main outcome measures : The outcomes included all-cause mortality and cause-specific mortality from CVD, cancer, and dementia. Statistical analyses performed : Multivariable Cox proportional hazards models were used to estimate adjusted hazard ratios (HRs) of all-cause mortality and cause-specific mortality. Results : During 1,608,856 person-years of follow-up (mean [SD] of 19.0 [4.2] years), 25,388 deaths occurred, including 7,069 deaths from CVD, 7,030 deaths from cancer, and 3,279 deaths from dementia. After adjustment for a variety of covariates, compared with no chocolate consumption, the HRs (95% CI) for all-cause mortality were 0.95 (0.92 to 0.98), 0.93 (0.89 to 0.96), 0.97 (0.90 to 1.04), and 0.90 (0.84 to 0.97) for Conclusions : The results suggest a modest inverse association of chocolate consumption with mortality from all causes, CVD, or dementia, specifically for moderate chocolate consumption of 1 to 3 servings/wk. |
| Disponible en ligne : | Oui |
| En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/article/pii/S2212267222012564 |
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