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Titre : | Prevalence of Polypharmacy in Patients With Vestibular and Balance Complaints (2023) |
Auteurs : | Seth S. Jeong ; Tiffany Chen, T ; Tatianna A. Timor ; Adrienne L. Busch ; Ted A. Meyer ; Shaun A. Nguyen ; Habib G. Rizk |
Type de document : | Article |
Dans : | Ear and hearing (Vol. 44, n°3, Mai-Juin 2023) |
Article en page(s) : | p. 506-517 |
Note générale : | 10.1097/AUD.0000000000001292 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Audiométrie ; Polypharmacie ; Vertige |
Résumé : |
Objectives: To determine the prevalence of polypharmacy in patients presenting with dizziness to a tertiary neurotology clinic and analyze the association between polypharmacy and clinical characteristics.
Design: Retrospective, cross-sectional review. Demographics, symptoms, diagnoses, medications, audiometry, dizziness handicap index (DHI) scores, and cognitive failure questionnaire (CFQ) scores were extracted from charts of patients seen as new patients from September 1, 2019, to March 31, 2020, with a primary complaint of dizziness. Results: A total of 382 patients were included. More than two-thirds of the patients (n = 265, 69.4%) met criteria for polypharmacy (>=5 medications), of which most (n = 249, 94.0%) were prescribed a potentially ototoxic drug. Approximately 10% of patients were taking five or more ototoxic medications (oto-polypharmacy). Polypharmacy was correlated to age and was more common for patients with diabetes, hypertension, other cardiovascular comorbidities, and depression (odds ratio [OR], 3.73-6.67; p Conclusions: The prevalence of polypharmacy in patients with vestibular disorders is high. Some of the medications that patients are on are also potentially ototoxic at variable degrees. Polypharmacy is more common when lightheadedness is one of the dizziness descriptors and seems to be associated with worse scores on patient-reported outcome measures (DHI, CFQ). Medication reconciliation and multidisciplinary involvement could help to better address polypharmacy in this patient population. However, further investigation is needed to elucidate polypharmacy's role in symptom presentation, vestibular testing results, and therapeutic strategies. |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=yrovftz&AN=00003446-202305000-00007 |