Login
Communauté Vinci
Extérieur
Si votre nom d'utilisateur ne se termine pas par @vinci.be ou @student.vinci.be, utilisez le formulaire ci-dessous pour accéder à votre compte de lecteur.
Titre : | Pattern of relapse following three-field lymphadenectomy of esophageal carcinoma and related factors predictive of recurrence (2023) |
Auteurs : | Z.-C. Xu ; B.-A. Su ; J.-C. Li ; W.-F. Cheng ; J. Chen |
Type de document : | Article |
Dans : | Cancer/Radiothérapie (Vol. 27, n° 3, Mai 2023) |
Article en page(s) : | p. 189-195 |
Note générale : | https://doi.org/10.1016/j.canrad.2022.09.001 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Carcinome épidermoïde ; Métastase tumorale ; Oesophagectomie ; Période postopératoire ; Radiothérapie ; Tumeurs de l'oesophage |
Mots-clés: | Carcinome épidermoïde de l'oesophage |
Résumé : |
Purpose
For treatment of esophageal carcinoma, the optimal postoperative radiotherapy target volume after three-field lymph node dissection (3-FLD) had not been determined. We analyzed local recurrence pattern of thoracic esophageal carcinoma and risk factors of lymph node recurrence after 3-FLD without prophylactic radiotherapy. Material and methods We reviewed 1282 patients with thoracic esophageal squamous cell carcinoma (ESCC) who were treated with 3-FLD without radiotherapy from 2010 to 2018 and analysed local recurrence patterns and risk factors of lymph node recurrence, in order to provide a reference for determination of the radiotherapy target volume for thoracic ESCC. Results The lymph node recurrence accounted for 91.0% of treatment failures. The mediastinal, cervical and abdominal lymph node recurrence accounted for 84.92%, 36.07% and 22.30%, respectively (χ2 = 264.776, P = 0.000). The superior, middle and inferior mediastinal lymph node recurrence rates were 67.54%, 27.87% and 0.98%, respectively (χ2 = 313.600, P = 0.000). Cervical metastases were significantly associated with N stage and Preoperative cervical lymph node status. Abdominal metastases were significantly associated with the number of preoperative abdominal lymph node metastases (LNM), tumor location and N stage. Conclusions The main pattern of local-regional recurrence might be lymph node metastasis after radical 3-FLD without radiotherapy in esophageal carcinoma. The dangerous lymph node recurrence regions included neck, superior and middle mediastinum. The abdominal areas might be irradiated for lower TEC patients with preoperative abdominal LNM. |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/article/pii/S1278321823000100 |