Login
Communauté Vinci
Extérieur
Si votre nom d'utilisateur ne se termine pas par @vinci.be ou @student.vinci.be, utilisez le formulaire ci-dessous pour accéder à votre compte de lecteur.
Titre : | Effects of omega-3 supplementation on serum albumin, pre-albumin and the CRP/albumin ratio in hospitalized patients: a systematic review and meta-analysis (2023) |
Auteurs : | Amir Bagheri ; Sanaz Soltani ; Farzaneh Asoudeh ; Ahmad Esmaillzadeh |
Type de document : | Article |
Dans : | Nutrition reviews (Vol. 81, n°3, March 2023) |
Article en page(s) : | p. 237-251 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Acides gras omega-3 ; Albumines ; Compléments alimentaires ; Dialyse ; Huiles de poisson ; Hypoalbuminémie ; Microbiome gastro-intestinal ; Préalbumine ; Protéine C-réactive ; Sérumalbumine ; Traitement médicamenteux |
Résumé : |
Context: Low serum albumin and pre-albumin concentrations are associated with edema, infection, thrombosis, heart failure, and mortality.
Objective: This comprehensive systematic review and meta-analysis of clinical trials was conducted to summarize the available findings on the impact of omega-3 supplementation on albumin, pre-albumin, and the C-reactive protein/albumin ratio in hospitalized patients. Data Sources: PubMed, Web of Science, Scopus, and Google Scholar databases were searched from January 1990 to October 2021. Data Extraction: Extracted data from 50 randomized controlled trials (RCTs) with a total number of 3196 participants were analyzed using the random-effects model. The dose-dependent effect was also evaluated. Data Analysis: Oral omega-3 supplementation significantly increased serum albumin concentrations in patients with cancer (weighted mean difference [WMD]: 0.19; 95% CI: 0.05, 0.33, P= 0.006), patients on dialysis (WMD: 0.14; 95% CI: 0.01, 0.28, P= 0.042), and those with hypoalbuminemia (WMD: 0.38; 95% CI: 0.03, 0.72, P=0.033); however, there was no significant effect among patients with gastrointestinal or hepatologic diseases. Moreover, each 1000mg/day increase in oral omega-3 supplementation resulted in elevated serum albumin levels in cancer patients (WMD: 0.15; 95% CI: 0.07, 0.24, P Conclusions: Overall, omega-3 fatty acids supplementation resulted in a favorable change in serum albumin and pre-albumin concentrations in hospitalized patients. |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://academic.oup.com/nutritionreviews/article/81/3/237/6658389 |