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Titre : | Prevalence of Neuropsychiatric Disorders in Duchenne and Becker Muscular Dystrophies: A Systematic Review and Meta-analysis (2022) |
Auteurs : | Carlos Pascual-Morena ; Iván Cavero-Redondo ; Sara Reina-Gutiérrez ; Alicia Saz-Lara ; José Francisco López-Gil ; Vicente Martínez-Vizcaíno |
Type de document : | Article |
Dans : | Archives of Physical Medicine and Rehabilitation (Vol. 103, n° 12, 2022) |
Article en page(s) : | p. 2444-2453 |
Note générale : | https://doi.org/10.1016/j.apmr.2022.05.015 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Dystrophies musculaires ; Maladie neuromusculaire ; Myopathie de Duchenne ; Réadaptation ; Trouble déficitaire de l'attention avec ou sans hyperactivité ; Trouble dépressif ; Trouble du spectre autistique (TSA) ; Trouble obsessionnel compulsif (TOC) ; Troubles anxieux |
Résumé : |
Objective
To estimate the prevalence of neuropsychiatric disorders, including autism spectrum disorders (ASDs), attention-deficit hyperactivity disorder (ADHD), depression, anxiety disorders, and obsessive-compulsive disorder (OCD), in populations with Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD). Data Sources MEDLINE (via PubMed), Scopus, Web of Science, and Cochrane Library from inception to November 2021. Study Selection Observational studies of individuals with DMD or BMD that estimated the prevalence of ASDs, ADHD, depression, anxiety disorders, and OCD in each population. Data Extraction A random-effects meta-analysis was performed on each outcome and each population (ie, DMD, BMD). Data Synthesis Twenty-three studies were included in the meta-analysis. In DMD, there was a prevalence of 7.0% of ASDs, 18.0% of ADHD, 11.0% of depression, 24.0% of anxiety disorders, and 12.0% of OCD. Furthermore, in BMD, there was a prevalence of 6.0% of ASDs, 28.0% of ADHD, 7.0% of depression, 25.0% of anxiety disorders, and 7.0% of OCD. Conclusions The prevalence of these neuropsychiatric disorders is higher among patients with DMD or BMD than among the general population, and the presence of these disorders may negatively influence optimal medical management. |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/article/pii/S0003999322004725 |