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Titre : | Despite the increase of serum CA 19-9, complete metabolic response and tumoral calcifications in PET/CT: Could it be a tumor stunning after chemotherapy? (2022) |
Auteurs : | G. Alçin ; E. Arslan ; N. Ergül ; T. Aksoy ; G. Tatar ; T.F. Çermik |
Type de document : | Article |
Dans : | Médecine nucléaire (vol. 46, n°4, Août 2022) |
Article en page(s) : | p. 191-193 |
Note générale : | https://doi.org/10.1016/j.mednuc.2022.02.003 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Adénocarcinome ; Chimiothérapie ; Fluorodésoxyglucose F18 |
Mots-clés: | Adénocarcinome gastrique non mucineux ; Étourdissement tumoral ; CA 19-9 ; FDG PET/CT ; Calcification tumorale |
Résumé : | A 74-year-old male patient with a history of nausea, vomiting, and loss of appetite revealed thickening of the antrum and pylorus in gastroscopy and non-mucinous adenocarcinoma was diagnosed in the biopsy. The patient underwent 18F-FDG PET/CT for staging. PET/CT showed intense FDG uptakes in the primary lesion, locoregional lymph nodes and liver metastases. After 5-fluorouracil based chemotherapy, a complete metabolic response in metastatic liver lesions, lymph nodes, and the primary tumor was detected. Furthermore, tumor calcifications were observed in the liver and locoregional lymph node metastases. Although a complete response, there was a 40 percent serum CA 19-9 level increase. During the follow-up, intense FDG uptake was observed in the calcified metastatic liver lesions and some lymph nodes, similar to the continuous increase in serum CA 19-9 levels. Ascites, multiple metastatic lung nodules and metabolic progression in liver lesions were observed on PET/CT in the patient who continued to receive chemotherapy. |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.em-premium.com/article/1533737 |