Login
Communauté Vinci
Extérieur
Si votre nom d'utilisateur ne se termine pas par @vinci.be ou @student.vinci.be, utilisez le formulaire ci-dessous pour accéder à votre compte de lecteur.
Titre : | The prognostic value of 18F-FDG PET/CT taken immediately after completion of radiotherapy for lung cancer treated with concurrent chemoradiotherapy: A pilot study (2022) |
Auteurs : | A. Harigai ; A.I. Saito ; T. Inoue ; M. Suzuki ; Y. Namba ; Y. Suzuki ; F. Makino ; O. Nagashima ; S. Sasaki ; K. Sasai |
Type de document : | Article |
Dans : | Cancer/Radiothérapie (vol. 26, no. 5, Septembre 2022) |
Article en page(s) : | p. 711-716 |
Note générale : | https://doi-org.ezproxy.vinci.be/10.1016/j.canrad.2022.01.006 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Chimioradiothérapie ; Fluorodésoxyglucose F18 ; Tomographie par émission de positons ; Tumeurs du poumon |
Mots-clés: | tomographie par ordinateur au fluorodésoxyglucose F-18 ; Cancer du poumon non à petites cellules ; Chimioradiothérapie simultanée |
Résumé : | Purpose The prognostic value of F-18 fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) taken immediately after completion of radiotherapy in lung cancer patients is not well known. The purpose of this study is to assess the prognostic value of PET/CT taken immediately after completion of radiotherapy in lung cancer patients. Materials and methods Patients with primary lung cancer planned to undergo concurrent chemoradiotherapy were enrolled. Patients underwent PET/CT scans at 3 time points: before radiotherapy, within 24hours of completing radiotherapy (im-PET/CT), and 2?9 months after radiotherapy (post-PET/CT). Maximum standardized uptake value (SUVmax) was obtained. A post-PET/CT-SUVmax cut-off of 2.5 was determined as radiotherapy success. Results Nineteen patients were enrolled. im-PET/CT-SUVmax for patients in the high post-PET/CT-SUVmax group was significantly higher than that of the low group (P=0.004). Receiver operator curve analysis indicated that im-PET/CT-SUVmax of 4.35 was an optimal cut-off value to discriminate between the two groups. Multivariable analysis showed that a high im-PET/CT-SUVmax was significantly associated with a high post-PET/CT-SUVmax (P=0.003). Conclusion PET/CT-SUVmax taken immediately following radiotherapy was associated with that evaluated 2?9 months after radiotherapy. |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/article/pii/S1278321822000440 |