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Titre : | Frailty and Falls in People Living With Multiple Sclerosis (2022) |
Auteurs : | Tobia Zanotto ; Irina Galperin ; Anat Mirelman ; Shahar Yehezkiyahu ; John Estes ; Lingjun Chen ; Keren Regev ; Tanja Schmitz-Hübsch ; Paul Friedemann ; Sharon G. Lynch ; Abiodun E. Akinwuntan ; Hannes Devos ; Jeffrey M. Hausdorff ; Jacob J. Sosnoff |
Type de document : | Article |
Dans : | Archives of Physical Medicine and Rehabilitation (Vol. 103, n° 5, 2022) |
Article en page(s) : | p. 952-957 |
Note générale : | https://doi.org/10.1016/j.apmr.2021.10.025 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Chutes accidentelles ; Réadaptation ; Sclérose en plaques ; Vieillissement |
Résumé : |
Objective
To explore the association between frailty and history of falls in people living with multiple sclerosis (MS). Design Secondary analysis. Setting University research laboratories in the United States and Israel. Participants A total of 118 people (N=118) with relapsing-remitting MS (mean age, 48.9±10.0 years; 74.6% female; Expanded Disability Status Scale [EDSS] range, 1.0-6.0) were studied in this cross-sectional analysis. Intervention Not applicable. Main Outcome Measures A frailty index was calculated from 40 health deficits by following standard validated procedures. The number of falls (12-month history) was recorded. Results Overall, 33.9%, 29.7%, and 36.4% of participants were classified as nonfrail, moderately frail, and severely frail, respectively. The frailty index was significantly correlated (ρ=0.37, P<.001 with higher scores on the edss. in univariable negative binomial regression analysis frailty index was associated a number of falls rate ratio ci p after adjustment for age sex and edss remained strongly history> Conclusions The current study identifies a significant relationship between frailty and history of falls in MS, independent of age, sex, and disease severity. These findings support the notion that frailty is a syndrome related to but independent of disability in MS. |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/article/pii/S0003999321015768#! |