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Titre : | Real-time exercise reduces impaired cardiac function in breast cancer patients undergoing chemotherapy: A randomized controlled trial (2022) |
Auteurs : | Wei-Pang Chung ; Hsin-Lun Yang ; Ya-Ting Hsu ; Ching-Hsia Hung ; Ping-Yen Liu ; Yen-Wen Liu ; Shih-Hung Chan ; Kun-Ling Tsai |
Type de document : | Article |
Dans : | Annals of Physical and Rehabilitation Medicine (Vol. 65, n° 2, March 2022) |
Article en page(s) : | 8 p. |
Note générale : | https://doi.org/10.1016/j.rehab.2021.101485 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Chimiothérapie ; Essais cliniques comme sujet ; Exercice physique ; Tests de la fonction cardiaque ; Tumeurs du sein |
Résumé : | Background Previous studies have reported that chemotherapy results in substantial long-term risk of heart failure. Exercise ameliorates exercise responses and exercise tolerance in patients receiving chemotherapy. The cardioprotective effect of real-time exercise in breast cancer is still unclear. Objectives The aim of the present study was to determine the effect of real-time moderate-to-high?intensity exercise training in women with breast cancer undergoing chemotherapy and to follow up on parameters of cardiac function and exercise capacity at different times. We hypothesized that early moderate-to-high?intensity exercise training has beneficial effects on cardiac function in women with breast cancer undergoing chemotherapy. Methods This was a randomized controlled study that included 32 women randomly allocated into the control or exercise group. Exercise began with the first cycle of chemotherapy, and the training program was maintained during chemotherapy with 2 to 3 sessions per week for 3 months. Patients were instructed to perform moderate-to-high?intensity training with aerobic and resistance training. Outcome measurements were echocardiography and cardiopulmonary exercise test. The primary outcome was the change in left ventricle ejection fraction (LVEF). The secondary outcome was peak oxygen consumption (peak VO2). Results The control group showed lower cardiac systolic function than the exercise group [mean (SD) LVEF 62% (2) and 70% (5), P |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/article/pii/S1877065721000038 |