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Titre : | Evaluating the Role of Otologic Biomarkers to Differentiate Meniere's Disease and Vestibular Migraine (2022) |
Auteurs : | James J. Naples ; Drew Soda ; Kahlil Rahman ; Michael J. Ruckenstein ; Kourosh Parham |
Type de document : | Article |
Dans : | Ear and hearing (Vol.43, n°2, Mars-avril 2022) |
Article en page(s) : | p. 699-702 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Maladie de Ménière ; Marqueurs biologiques ; MIGRAINE VESTIBULAIRE ; Vertige |
Résumé : |
Objective: To evaluate the role for prestin and otolin-1 as biomarkers for differentiating Meniere's disease (MD) from vestibular migraine (VM).
Study Design: It is a cross-sectional, cohort study. Results: There were 19 MD and 11 VM patients. In the 19 MD patients, the mean prestin level was 2.33 ng/ml compared to 0.64 ng/ml in VM patients (p = 0.238). Otolin-1 levels in MD patients were 109.67 pg/ml, while in VM patients, otolin-1 levels were 30.9 pg/ml (p = 0.102). In MD patients, prestin levels were correlated with word recognition scores, being strongest when prestin >2 ng/ml (rho = 0.9; p = 0.019). Conclusions: Prestin and otolin-1 levels differed between MD patients relative to VM patients. The relationship between prestin and word recognition scores in MD suggests that there may be a role for prestin as a marker for inner ear function, but its role in differentiating MD from VM remains to be elucidated. |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=yrovftx&AN=00003446-202203000-00041 |