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Titre : | Correlation between functional capacity and oxidative stress and inflammation in hemodialysis patients (2021) |
Auteurs : | Ítalo Caldas Silva ; Ítalo Caldas Silva ; Débora Fortes Marizeiro ; Elizabeth De Francesco Daher ; Tainá Veras de Sandes-Freitas ; Gdayllon Cavalcante Meneses ; Gabriela Freire Bezerra ; Alexandre Braga Libório ; Alice Maria Costa Martins ; Nataly Gurgel Campos |
Type de document : | Article |
Dans : | Journal of Bodywork and Movement Therapies (Vol. 27, July 2021) |
Article en page(s) : | p. 339-343 |
Note générale : | https://doi.org/10.1016/j.jbmt.2021.01.002 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Dialyse rénale ; Études transversales ; Femmes ; Hommes ; Humains ; Inflammation ; Malonaldéhyde ; Marqueurs biologiques ; Stress oxydatif |
Mots-clés: | Chronic kidney disease ; Renal dialysis ; Biomarkers ; 6-Min walk test |
Résumé : | Introduction Patients with chronic kidney disease (CKD) may present impaired functional capacity due to peripheral muscle involvement. Oxidative stress and inflammation are probably involved in this pathophysiology. This study aimed to evaluate the association between functional capacity and biomarkers of oxidative stress as well as biomarkers of inflammation in patients under chronic hemodialysis therapy. Method Cross-sectional study including 41 patients from a single hemodialysis center. Functional capacity was assessed through the 6-min walk test (6MWT). The assessed blood biomarkers were: malondialdehyde (MDA) (oxidative stress, TBARS method) and angiopoietin-2 (Ang-2) (inflammation, ELISA). The influence of gender on impairment of functional capacity was further explored. Results There was an inversely proportional correlation between the 6MWD and MDA (r = -,322 and p = 0.040) and Ang-2 (r = -, 376 and p = 0.016) values. 6MWD was 370.9 + 101.2 m and 391.4 + 108.2 m in women and men, respectively (p |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/article/pii/S1360859221000024 |