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Titre : | Effectiveness of various methods of home fortification in under-5 children: where they work, where they do not. A systematic review and meta-analysis (2021) |
Auteurs : | Bahareh Nikooyeh ; Tirang R. Neyestani |
Type de document : | Article |
Dans : | Nutrition reviews (Vol. 79, n°4, April 2021) |
Article en page(s) : | p. 445-461 |
Note générale : | doi:10.1093/nutrit/nuaa087 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Développement de l'enfant ; Micronutriments |
Mots-clés: | les compléments nutritifs à base de lipides ; supplémentation alimentaire à domicile |
Résumé : |
Context:
The common approaches of home fortification (HF) for prevention and/or treatment of micronutrient deficiencies are micronutrient powders (MNPs), foodlets, and lipid-based nutrient supplements (LNSs). There are mixed results for the impact of HF on growth and nutritional status of young children. Objective: This systematic review was prepared in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines to evaluate current evidence from randomized controlled trials including children younger than 5 years to assess the effect of strategies of HF on growth and micronutrient status. Methods: The MEDLINE, PubMed, Embase, Cochrane Library, and Google Scholar databases were searched to July 2018. A total of 1301 studies were found in a preliminary search. After screening of titles and abstracts, 30 studies were selected. Results: Treatment with MNPs, foodlets, and LNSs effectively increased hemoglobin concentrations by at least 2.52 g/L, 4.59 g/L, and 4.4 g/dL, respectively, as compared with a control. There was a significant decrease in risk of anemia development after foodlet intervention compared with a control or iron drops (odds ratio, 0.27; 95%CI, 0.100.74; P = 0.01). However, these interventions did not result in any significant improvement in z-scores for changes of height for age, weight for age, and weight for height. The results indicated that MNP (7.16; 95%CI, 0.3114.01; P = 0.04) and foodlet treatment (4.92; 95%CI, 0.289.57; P = 0.04) could increase serum zinc levels. However, none of the home fortification methods improved vitamin A status in the target group. Conclusion: Home fortification can be used as an effective method to improve hemoglobin, iron, and zinc status, although in this study it had no effect on vitamin A or anthropometric indicators of the target population. More investigations are warranted for newer approaches of HF to improve a broader range of micronutrients as well as child growth indices and for evaluation of the coverage, compliance, and consistency of such interventions at the population level. |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://academic.oup.com/nutritionreviews/article/79/4/445/5917817 |