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Titre : | The effect of pro/synbiotics on postoperative infections in colorectal cancer patients: A systematic review and meta-analysis (2021) |
Auteurs : | Juan Zeng ; Yichun Ji ; Bingxue Liang ; et al. |
Type de document : | Article |
Dans : | Complementary Therapies in Clinical Practice (Vol. 43, May 2021) |
Article en page(s) : | 101370 |
Note générale : | https://doi.org/10.1016/j.ctcp.2021.101370 |
Langues: | Anglais |
Résumé : | In 1954, the term "probiotics" was coined by Ferdinand Vergin in his article. Although there are many clinical reports on the use of pro/synbiotics and other microbial preparations to prevent postoperative infections and related complications in patients with Colorectal cancer (CRC), their effectiveness remains divided. Therefore, we collected relevant high-quality randomized controlled trial (RCT) studies and conducted systematic review and meta-analysis. We electronically searched online databases (the PubMed, EMBASE, MEDLINE, Cochrane Central Register of Controlled Trials (CENTRAL), Allied and Alternative Medieine (AMED), China National Knowledge Infrastructure (CNKI), Wanfang, and Weipu) for literature published until December 2020. These reports were rigorously screened, and the data extracted, assessed for risk of bias (ROB), and subjected to meta-analysis and subgroup analysis. Postoperative infections were the main criteria for outcomes. Nineteen high-quality articles were included, involving 1975 patients. Compared with the control group, the pro/synbiotics group had reduced total postoperative infections ((odds ratio)OR = 0.28, 95% (confidence interval)CI: 0.20; 0.39, p |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/article/abs/pii/S1744388121000694#! |