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Titre : | Effectiveness of topical ozonated oil in severe osteoarthritis: A randomised, triple-blinded, placebo-controlled study (2021) |
Auteurs : | Ana Paula Anzolin ; Diego da Silva Collares ; Renato Tadeu dos Santos ; et al. |
Type de document : | Article |
Dans : | Complementary Therapies in Clinical Practice (Vol. 43, May 2021) |
Article en page(s) : | 101351 |
Note générale : | https://doi.org/10.1016/j.ctcp.2021.101351 |
Langues: | Anglais |
Résumé : |
Background
Osteoarthritis is highly prevalent and a common locomotory disorder in the elderly. The treatments aim improves the quality of life. We aimed to evaluate the effectiveness of topical ozonated oil in relieving pain in patients with osteoarthritis. Design A placebo-controlled, triple-blind, randomised controlled trial including osteoarthritis patients older than 50 years. Interventions Eighty patients were randomly divided into two groups: treatment (ozonated oil) and placebo (non-ozonated oil). The oils were used twice a day for 60 days. Evaluations were performed using WOMAC (Western Ontario and McMaster Universities) and VAS (visual analogue scale) and laboratory analysis. Results Pain relief was observed in all groups except in the placebo group where patients are diagnosed with severe osteoarthritis (degree 4) (p-value treatment and placebo group: 0.021 and 0.345, respectively). Conclusions For the first time, the pain relief in patients with severe osteoarthritis was demonstrated by the use of topical ozonated oil. |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/article/abs/pii/S1744388121000505#! |