Login
Communauté Vinci
Extérieur
Si votre nom d'utilisateur ne se termine pas par @vinci.be ou @student.vinci.be, utilisez le formulaire ci-dessous pour accéder à votre compte de lecteur.
Titre : | Hearing loss is associated with hippocampal atrophy and high cortisol/dehydroepiandrosterone sulphate ratio in older adults (2021) |
Auteurs : | Bunya Kuze ; Mitsuhiro Aokia ; Hiroshi Okuda ; Hiromasa Ishihara ; Hisamitsu Hayashi ; Toshimitsu Ohashi ; Takesumi Nishihori |
Type de document : | Article |
Dans : | International Journal of Audiology IJA (Vol. 60, n°4, Avril 2021) |
Article en page(s) : | p. 293-299 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Cytokines ; Hippocampe humain ; Hormones corticosurrénaliennes ; Perte d'audition ; Sujet âgé |
Résumé : |
Objectives
Hearing loss (HL) has been recognised as a prodromal symptom of cognitive disorder with aging. It is still uncertain if HL leads to cognitive impairment directly or through an indirect mechanism. Design Participants of this study underwent an auditory test, blood tests, and brain MRI. The atrophy rate of the hippocampus (HP) was calculated using voxel-based specific areas. A partial correlation analysis whilst controlling for the effect of age was performed to analyse the factors affecting hearing levels and HP atrophy rate (HP%). Study sample Thirty-six older adults with hearing impairment Results The group of participants with moderate or severe HL (n = 22) had higher cortisol/dehydroepiandrosterone sulphate (C/D) ratio, geriatric depression score (GDS) and HP% than the mild HL or normal hearing group (n = 14, p Conclusions Our results suggest that the HL is associated with the atrophy of HP and high C/D ratios in older adults; however, HL may not be causally related to hippocampal atrophy. |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.tandfonline.com/doi/full/10.1080/14992027.2020.1831703 |