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Titre : | Efficacy of fish oil and its components in the management of psoriasis: a systematic review of 18 randomized controlled trials (2020) |
Auteurs : | Xi Chen ; Seokgyeong Hong ; Xiaoying Sun ; Wenbin Xu ; Hongjin Li ; Tian Ma ; Qi Zheng ; Huaibo Zhao ; Yaqiong Zhou ; Yan Qiang ; Bin Li ; Xin Li |
Type de document : | Article |
Dans : | Nutrition reviews (Vol. 78, n° 10, October 2020) |
Article en page(s) : | p. 827840 |
Note générale : | doi:10.1093/nutrit/nuz098 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Acides gras insaturés ; Acides gras omega-3 ; Huiles de poisson ; Psoriasis |
Résumé : |
Context:
Fish oil and omega-3 polyunsaturated fatty acids (ω-3 PUFAs) have anti-inflammatory properties, but their effect on psoriasis and its comorbidities remains inconclusive. Objective: The aim of this quantitative systematic review was to evaluate the efficacy and safety of fish oil and its components in the treatment of psoriasis and its comorbidities. Data Sources: PubMed, Embase, Cochrane Central Register of Controlled Trials, China Network Knowledge Infrastructure, China Science and Technology Journal Database, and Wanfang databases were searched from inception to March 30, 2019. Study Selection: Randomized controlled trials were eligible for inclusion if they measured the effect of fish oil and its components in the treatment of patients with psoriasis. Data Extraction: Eighteen randomized controlled trials involving 927 study participants were included. Results: Monotherapy with fish oil or ω-3 PUFAs had no effect on the Psoriasis Area and Severity Index (PASI) score (P = 0.47), lesion area (P = 0.34), or pruritus (P = 0.62). Fish oil or ω-3 PUFAs combined with conventional treatments, however, resulted in a decreased PASI score (mean difference [MD], −3.92; 95%CI, −6.15 to −1.69; P = 0.0006) and lesion area (MD, −30.00; 95%CI, −33.82 to −26.18; P Conclusions: Overall, when combined with conventional treatments, fish oil and its components may have beneficial effects on psoriasis and its comorbidities, including obesity, cardiovascular disease, and metabolic disease. |
Disponible en ligne : | Oui/Non |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://academic.oup.com/nutritionreviews/article/78/10/827/5717452 |
Exemplaires (1)
Cote | Support | Localisation | Section | Disponibilité |
---|---|---|---|---|
Nutrition reviews. Vol. 78, n° 10 (October 2020) | Périodique papier | Woluwe | Espace revues | Consultation sur place uniquement Exclu du prêt |