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Titre : | Effect of Rehabilitation Treatments on Disability in Persons With Disorders of Consciousness: A Propensity Score Study (2020) |
Auteurs : | Davide Sattin ; Matilde Leonardi ; Barbara Nelli |
Type de document : | Article |
Dans : | Archives of Physical Medicine and Rehabilitation (Vol. 101, n° 1, 2020) |
Article en page(s) : | p. 95-105 |
Note générale : | https://doi.org/10.1016/j.apmr.2019.07.010 |
Langues: | Anglais |
Descripteurs : |
HE Vinci État végétatif persistant ; Réadaptation ; Score de propension |
Résumé : |
Objective
To evaluate the effects of rehabilitation (physical and cognitive) treatments on the diagnosis severity and Disability Rating Scale (DRS) scores, adjusted for a number of potential confounders measured at baseline, in a large cohort of patients with disorders of consciousness across time. Design and Setting An observational, longitudinal (2 evaluations), multicenter project was made in 90 Italian centers. Participants Patients (N=364) with a diagnosis of disorders of consciousness. Main Outcome Measures Primary outcome was the severity of diagnosis, expressed on an ordinal scale (Other A total of 364 subjects having a complete set of demographic, clinical, and pharmacologic data were included in the propensity score (PS) analysis. Results showed that the rehabilitation treatments (physical and cognitive) reduced the clinical worsening over time in both severity diagnosis and DRS (around 6.5 points) in patients with disorders of consciousness across different propensity score strategies (ie, PS matching, PS adjustment, and PS-weighted procedures). In addition, cognitive protocols seem to be limited to patients with a median value of DRS=23. Conclusions Our propensity score analysis suggests that rehabilitation treatment protocols seem effective and should be applied to a broader spectrum of patients with disorders of consciousness. |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/article/pii/S0003999319310019 |