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Titre : | Impaired Executive Function Can Predict Recurrent Falls in Parkinson's Disease (2014) |
Auteurs : | Margaret K. Mak ; Adrian Wong ; Marco Y.C. Pang |
Type de document : | Article |
Dans : | Archives of Physical Medicine and Rehabilitation (2014/12, 2014) |
Article en page(s) : | p. 2390-2395 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Etudes prospectives ; Fonctions exécutives ; Maladie de Parkinson ; Rééducation et réadaptation |
Mots-clés: | Accidental falls ; Chutes accidentelles ; Executive function ; Parkinson disease ; Prospective Studies |
Résumé : |
Objective To examine whether impairment in executive function independently predicts recurrent falls in people with Parkinson's disease (PD). Design Prospective cohort study. Setting University motor control research laboratory. Participants A convenience sample of community-dwelling people with PD (N=144) was recruited from a patient self-help group and movement disorders clinics. Interventions Not applicable. Main Outcome Measures Executive function was assessed with the Mattis Dementia Rating Scale Initiation/Perseveration (MDRS-IP) subtest, and fear of falling (FoF) with the Activities-specific Balance Confidence (ABC) Scale. All participants were followed up for 12 months to record the number of monthly fall events. Results Forty-two people with PD had at least 2 falls during the follow-up period and were classified as recurrent fallers. After accounting for demographic variables and fall history (P=.001), multiple logistic regression analysis showed that the ABC scores (P=.014) and MDRS-IP scores (P=.006) were significantly associated with future recurrent falls among people with PD. The overall accuracy of the prediction was 85.9%. With the use of the significant predictors identified in multiple logistic regression analysis, a prediction model determined by the logistic function was generated: Z = 1.544 + .378 (fall history) − .045 (ABC) − .145 (MDRS-IP). Conclusions Impaired executive function is a significant predictor of future recurrent falls in people with PD. Participants with executive dysfunction and greater FoF at baseline had a significantly greater risk of sustaining a recurrent fall within the subsequent 12 months. |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/article/pii/S0003999314010090 |