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Titre : | Body Mass Index Underestimates Adiposity in Persons With Multiple Sclerosis (2016) |
Auteurs : | Lara A. Pilutti ; Robert W. Motl |
Type de document : | Article |
Dans : | Archives of Physical Medicine and Rehabilitation (2016/3, 2016) |
Article en page(s) : | pp. 405412 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Composition corporelle ; Indice de masse corporelle ; Rééducation et réadaptation ; Sclérose en plaques |
Mots-clés: | Body composition ; Body mass index ; Multiple sclerosis ; Obesity |
Résumé : |
Objectives To examine the relation between body mass index (BMI) and adiposity assessed by dual-energy x-ray absorptiometry in persons with multiple sclerosis (MS) and non-MS controls as well as to determine the accuracy of standard and alternate BMI thresholds for obesity. Design Cross-sectional. Setting University research laboratory. Participants The sample included persons with MS (n=235) and controls (n=53) (N=288). Interventions Not applicable. Main Outcome Measures Main outcome measures included BMI, whole body soft tissue composition (ie, percent body fat [%BF], fat mass, and lean soft tissue mass), bone mineral content, and bone mineral density. Results We observed significant strong associations between BMI and sex-specific %BF in persons with MS and non-MS controls, and BMI explained ∼40% of the variance in %BF in both MS and control samples. Receiver operating characteristic curve analyses indicated that the standard BMI threshold for obesity (ie, 30kg/m2) had excellent specificity (93%100%) but poor sensitivity (37%44%) in persons with MS and non-MS controls. The BMI threshold that best identified %BF-defined obesity was 24.7kg/m2 in the MS sample and 25.1kg/m2 in the control sample. Conclusions We determined a strong association between BMI and adiposity; however, the current BMI threshold for classifying obesity underestimates true adiposity in persons with MS. A similar relation was observed between BMI and obesity in non-MS controls. The non-MS sample included primarily middle-aged women, and similar BMI-%BF misclassifications have been reported in these samples. |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/article/pii/S0003999315012356 |