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15 résultat(s) recherche sur le mot-clé 'Neoplasms' 
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Partager le résultat de cette recherche Faire une suggestionAn Evidence-Based Review of Cognitive Rehabilitation in Medical Conditions Affecting Cognitive Function / Donna Langenbahn in Archives of Physical Medicine and Rehabilitation, 2013/2 (2013)
Titre : An Evidence-Based Review of Cognitive Rehabilitation in Medical Conditions Affecting Cognitive Function Type de document : Article Auteurs : Donna Langenbahn ; Teresa Ashman ; Joshua Cantor Article en page(s) : pp. 271-286 Langues : Anglais (eng) Descripteurs : HE Vinci
Cognition ; Encephalite ; Epilepsie ; Lupus érythémateux disséminé ; Maladie de Huntington ; Maladie de Lyme ; Maladie de Parkinson ; Rééducation et réadaptation ; Revue de la littérature ; Syndrome d'immunodéficience acquise ; TumeursMots-clés : AIDS Anoxia Anoxie Encephalitis Hypoxie cérébrale Epilepsy Huntington disease Lyme disease Neoplasms Parkinson disease Review Lupus Erythematosus Systemic Résumé : Objectives
To perform a methodical review of the evidence available for the efficacy of cognitive rehabilitation in individuals with diagnosed medical conditions known to affect cognitive function, and to establish evidence-based recommendations for clinical practice, as appropriate.
Data Sources
Ovid Medline and PubMed literature searches were conducted using the terms cognition, cognitive, crossed with the terms rehabilitation, remediation, retraining, training, crossed with 11 medical diagnostic categories. Articles through December 2008 were accessed, with a resulting 2284 abstracts.
Study Selection
A total of 211 articles were selected from initial abstract review. These articles were then assessed by committee members, with agreement of at least 2 members, using 9 exclusion and 3 inclusion criteria. A total of 34 remaining articles were submitted to full review.
Data Extraction
Articles were reviewed under diagnostic categories using specific criteria recorded on structured data sheets. Classification was performed according to guidelines of the American Academy of Neurology, with agreement between 2 committee members necessary for final decisions.
Data Synthesis
Of the 34 studies fully evaluated, 1 was rated as class I, 6 as class II, 2 as class III, and 25 as class IV. Evidence within each diagnostic area was synthesized for the formulation of Practice Standards, Practice Guidelines, and Practice Options, as possible.
Conclusions
Two clinical practice recommendations were advanced, 1 each in the diagnostic areas of brain neoplasms and epilepsy/seizure disorders. Discussion included comments on the research status of the effectiveness of cognitive rehabilitation for cognitive deficits related to these medical conditions, as well as suggestions for future directions in research.Disponible en ligne : Oui En ligne : http://www.archives-pmr.org/article/S0003-9993%2812%2900931-8/abstract Permalink : https://bib.vinci.be/opac_css/index.php?lvl=notice_display&id=117390
in Archives of Physical Medicine and Rehabilitation > 2013/2 (2013) . - pp. 271-286[article] An Evidence-Based Review of Cognitive Rehabilitation in Medical Conditions Affecting Cognitive Function [Article] / Donna Langenbahn ; Teresa Ashman ; Joshua Cantor . - pp. 271-286.
Langues : Anglais (eng)
in Archives of Physical Medicine and Rehabilitation > 2013/2 (2013) . - pp. 271-286
Descripteurs : HE Vinci
Cognition ; Encephalite ; Epilepsie ; Lupus érythémateux disséminé ; Maladie de Huntington ; Maladie de Lyme ; Maladie de Parkinson ; Rééducation et réadaptation ; Revue de la littérature ; Syndrome d'immunodéficience acquise ; TumeursMots-clés : AIDS Anoxia Anoxie Encephalitis Hypoxie cérébrale Epilepsy Huntington disease Lyme disease Neoplasms Parkinson disease Review Lupus Erythematosus Systemic Résumé : Objectives
To perform a methodical review of the evidence available for the efficacy of cognitive rehabilitation in individuals with diagnosed medical conditions known to affect cognitive function, and to establish evidence-based recommendations for clinical practice, as appropriate.
Data Sources
Ovid Medline and PubMed literature searches were conducted using the terms cognition, cognitive, crossed with the terms rehabilitation, remediation, retraining, training, crossed with 11 medical diagnostic categories. Articles through December 2008 were accessed, with a resulting 2284 abstracts.
Study Selection
A total of 211 articles were selected from initial abstract review. These articles were then assessed by committee members, with agreement of at least 2 members, using 9 exclusion and 3 inclusion criteria. A total of 34 remaining articles were submitted to full review.
Data Extraction
Articles were reviewed under diagnostic categories using specific criteria recorded on structured data sheets. Classification was performed according to guidelines of the American Academy of Neurology, with agreement between 2 committee members necessary for final decisions.
Data Synthesis
Of the 34 studies fully evaluated, 1 was rated as class I, 6 as class II, 2 as class III, and 25 as class IV. Evidence within each diagnostic area was synthesized for the formulation of Practice Standards, Practice Guidelines, and Practice Options, as possible.
Conclusions
Two clinical practice recommendations were advanced, 1 each in the diagnostic areas of brain neoplasms and epilepsy/seizure disorders. Discussion included comments on the research status of the effectiveness of cognitive rehabilitation for cognitive deficits related to these medical conditions, as well as suggestions for future directions in research.Disponible en ligne : Oui En ligne : http://www.archives-pmr.org/article/S0003-9993%2812%2900931-8/abstract Permalink : https://bib.vinci.be/opac_css/index.php?lvl=notice_display&id=117390
Titre : Changes in Health Status Among Aging Survivors of Pediatric Upper and Lower Extremity Sarcoma: A Report From the Childhood Cancer Survivor Study Type de document : Article Auteurs : Neyssa Marina ; Mélissa Hudson ; Kendra Jones ; [et al.] Article en page(s) : pp. 1062-1073 Langues : Anglais (eng) Descripteurs : HE Vinci
Membre inférieur ; Membre supérieur ; Rééducation et réadaptation ; Survivants ; TumeursMots-clés : Lower extremity Neoplasms Sarcoma Sarcomes Survivors Upper extremity Résumé : Objective
To evaluate health status and participation restrictions in survivors of childhood extremity sarcomas.
Design
Members of the Childhood Cancer Survivor Study cohort with extremity sarcomas who completed questionnaires in 1995, 2003, or 2007 were included.
Setting
Cohort study of survivors of extremity sarcomas.
Participants
Childhood extremity sarcoma survivors (N=1094; median age at diagnosis, 13y (range, 0–20y); current age, 33y (range, 10–53y); 49% male; 87.5% white; 75% had lower extremity tumors) who received their diagnosis and treatment between 1970 and 1986.
Interventions
Not applicable.
Main Outcome Measures
Prevalence rates for poor health status in 6 domains and 5 suboptimal social participation categories were compared by tumor location and treatment exposure with generalized estimating equations adjusted for demographic/personal factors and time/age.
Results
In adjusted models, when compared with upper extremity survivors, lower extremity survivors had an increased risk of activity limitations but a lower risk of not completing college. Compared with those who did not have surgery, those with limb-sparing (LS) and upper extremity amputations (UEAs) were 1.6 times more likely to report functional impairment, while those with an above-the-knee amputation (AKA) were 1.9 times more likely to report functional impairment. Survivors treated with LS were 1.5 times more likely to report activity limitations. Survivors undergoing LS were more likely to report inactivity, incomes Conclusions
Treatment of lower extremity sarcomas is associated with a 50% increased risk for activity limitations; upper extremity survivors are at a 10% higher risk for not completing college. The type of local control influences health status and participation restrictions. Both of these outcomes decline with age.Disponible en ligne : Oui En ligne : https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/journal/a [...] Permalink : https://bib.vinci.be/opac_css/index.php?lvl=notice_display&id=117506
in Archives of Physical Medicine and Rehabilitation > 2013/6 (2013) . - pp. 1062-1073[article] Changes in Health Status Among Aging Survivors of Pediatric Upper and Lower Extremity Sarcoma: A Report From the Childhood Cancer Survivor Study [Article] / Neyssa Marina ; Mélissa Hudson ; Kendra Jones ; [et al.] . - pp. 1062-1073.
Langues : Anglais (eng)
in Archives of Physical Medicine and Rehabilitation > 2013/6 (2013) . - pp. 1062-1073
Descripteurs : HE Vinci
Membre inférieur ; Membre supérieur ; Rééducation et réadaptation ; Survivants ; TumeursMots-clés : Lower extremity Neoplasms Sarcoma Sarcomes Survivors Upper extremity Résumé : Objective
To evaluate health status and participation restrictions in survivors of childhood extremity sarcomas.
Design
Members of the Childhood Cancer Survivor Study cohort with extremity sarcomas who completed questionnaires in 1995, 2003, or 2007 were included.
Setting
Cohort study of survivors of extremity sarcomas.
Participants
Childhood extremity sarcoma survivors (N=1094; median age at diagnosis, 13y (range, 0–20y); current age, 33y (range, 10–53y); 49% male; 87.5% white; 75% had lower extremity tumors) who received their diagnosis and treatment between 1970 and 1986.
Interventions
Not applicable.
Main Outcome Measures
Prevalence rates for poor health status in 6 domains and 5 suboptimal social participation categories were compared by tumor location and treatment exposure with generalized estimating equations adjusted for demographic/personal factors and time/age.
Results
In adjusted models, when compared with upper extremity survivors, lower extremity survivors had an increased risk of activity limitations but a lower risk of not completing college. Compared with those who did not have surgery, those with limb-sparing (LS) and upper extremity amputations (UEAs) were 1.6 times more likely to report functional impairment, while those with an above-the-knee amputation (AKA) were 1.9 times more likely to report functional impairment. Survivors treated with LS were 1.5 times more likely to report activity limitations. Survivors undergoing LS were more likely to report inactivity, incomes Conclusions
Treatment of lower extremity sarcomas is associated with a 50% increased risk for activity limitations; upper extremity survivors are at a 10% higher risk for not completing college. The type of local control influences health status and participation restrictions. Both of these outcomes decline with age.Disponible en ligne : Oui En ligne : https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/journal/a [...] Permalink : https://bib.vinci.be/opac_css/index.php?lvl=notice_display&id=117506
Titre : Characterization of Cancer Patients in Inpatient Rehabilitation Facilities: A Retrospective Cohort Study Type de document : Article Auteurs : Jacqueline M. Mix ; Carl V. Granger ; Michael J. LaMonte Article en page(s) : pp. 971-980 Langues : Anglais (eng) Descripteurs : HE Vinci
Hospitalisation ; Rééducation et réadaptation ; Survivants ; TumeursMots-clés : Hospitalization Neoplasms Survivors Résumé : Objectives
To identify the types of cancer patients admitted to inpatient medical rehabilitation and to describe their rehabilitation outcomes.
Design
Retrospective cohort study.
Setting
U.S. inpatient rehabilitation facilities (IRFs).
Participants
Adult patients (N=27,952) with a malignant cancer diagnosis admitted to an IRF with a cancer-related impairment between October 2010 and September 2012 were identified from the Uniform Data System for Medical Rehabilitation database.
Interventions
Not applicable.
Main Outcome Measures
Demographic, medical, and rehabilitation characteristics for patients with various cancer tumor types were summarized using data collected from the Inpatient Rehabilitation Facility–Patient Assessment Instrument. Rehabilitation outcomes included the percentage of patients discharged to the community and acute care settings, and functional change from admission to discharge. Functional status was measured using the FIM instrument.
Results
Cancer patients constituted about 2.4% of the total IRF patient population. Cancer types included brain and nervous system (52.9%), digestive (12.0%), bone and joint (8.7%), blood and lymphatic (7.6%), respiratory (7.1%), and other (11.7%). Overall, 72% were discharged to a community setting, and 16.5% were discharged back to acute care. Patients with blood and lymphatic cancers had the highest frequency of discharge back to acute care (28%). On average, all cancer patient groups made significant functional gains during their IRF stay (mean FIM total change + SD, 23.5+16.2).
Conclusions
In a database representing approximately 70% of all U.S. patients in IRFs, we found that patients with a variety of cancer types are admitted to inpatient rehabilitation. Most cancer patients admitted to IRFs were discharged to a community setting and, on average, improved their function. Future research is warranted to understand the referral patterns of admission to postacute care rehabilitation and to identify factors that are associated with rehabilitation benefit in order to inform the establishment of appropriate care protocols.Disponible en ligne : Oui En ligne : https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/a [...] Permalink : https://bib.vinci.be/opac_css/index.php?lvl=notice_display&id=117751
in Archives of Physical Medicine and Rehabilitation > 2017/5 (2017) . - pp. 971-980[article] Characterization of Cancer Patients in Inpatient Rehabilitation Facilities: A Retrospective Cohort Study [Article] / Jacqueline M. Mix ; Carl V. Granger ; Michael J. LaMonte . - pp. 971-980.
Langues : Anglais (eng)
in Archives of Physical Medicine and Rehabilitation > 2017/5 (2017) . - pp. 971-980
Descripteurs : HE Vinci
Hospitalisation ; Rééducation et réadaptation ; Survivants ; TumeursMots-clés : Hospitalization Neoplasms Survivors Résumé : Objectives
To identify the types of cancer patients admitted to inpatient medical rehabilitation and to describe their rehabilitation outcomes.
Design
Retrospective cohort study.
Setting
U.S. inpatient rehabilitation facilities (IRFs).
Participants
Adult patients (N=27,952) with a malignant cancer diagnosis admitted to an IRF with a cancer-related impairment between October 2010 and September 2012 were identified from the Uniform Data System for Medical Rehabilitation database.
Interventions
Not applicable.
Main Outcome Measures
Demographic, medical, and rehabilitation characteristics for patients with various cancer tumor types were summarized using data collected from the Inpatient Rehabilitation Facility–Patient Assessment Instrument. Rehabilitation outcomes included the percentage of patients discharged to the community and acute care settings, and functional change from admission to discharge. Functional status was measured using the FIM instrument.
Results
Cancer patients constituted about 2.4% of the total IRF patient population. Cancer types included brain and nervous system (52.9%), digestive (12.0%), bone and joint (8.7%), blood and lymphatic (7.6%), respiratory (7.1%), and other (11.7%). Overall, 72% were discharged to a community setting, and 16.5% were discharged back to acute care. Patients with blood and lymphatic cancers had the highest frequency of discharge back to acute care (28%). On average, all cancer patient groups made significant functional gains during their IRF stay (mean FIM total change + SD, 23.5+16.2).
Conclusions
In a database representing approximately 70% of all U.S. patients in IRFs, we found that patients with a variety of cancer types are admitted to inpatient rehabilitation. Most cancer patients admitted to IRFs were discharged to a community setting and, on average, improved their function. Future research is warranted to understand the referral patterns of admission to postacute care rehabilitation and to identify factors that are associated with rehabilitation benefit in order to inform the establishment of appropriate care protocols.Disponible en ligne : Oui En ligne : https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/a [...] Permalink : https://bib.vinci.be/opac_css/index.php?lvl=notice_display&id=117751
Titre : Chemotherapy-Related Neuropathic Symptoms and Functional Impairment in Adult Survivors of Extracranial Solid Tumors of Childhood: Results From the St. Jude Lifetime Cohort Study Type de document : Article Auteurs : Kirsten Ness ; Kendra Jones ; Webb Smith ; [et al.] Article en page(s) : pp. 1451-1457 Langues : Anglais (eng) Descripteurs : HE Vinci
Rééducation et réadaptation ; TumeursMots-clés : Cisplatin Cisplatine Neoplasms Peripheral nervous system diseases Neuropathies périphériques Vincristine Résumé : Objectives
To ascertain prevalence of peripheral sensory and motor neuropathy, and to evaluate impairments in relation to function.
Design
St. Jude Lifetime Cohort Study, a clinical follow-up study designed to evaluate adverse late effects in adult survivors of childhood cancer.
Setting
A children's research hospital.
Participants
Eligibility required treatment for an extracranial solid malignancy between 1962 and 2002, age ≥18 years, ≥10 years postdiagnosis, and no history of cranial radiation. Survivors (N=531) were included in the evaluation with a median age of 32 years and a median time from diagnosis of 25 years.
Interventions
Not applicable.
Main Outcome Measures
Primary exposure measures were cumulative doses of vinca-alkaloid and platinum-based chemotherapies. Survivors with scores ≥1 on the sensory subscale of the Modified Total Neuropathy Score were classified with prevalent sensory impairment. Those with sex-specific z scores of ≤−1.3 for dorsiflexion strength were classified with prevalent motor impairment. Participants completed the 6-minute walk test (endurance), the Timed Up & Go test (mobility), and the Sensory Organization Test (balance).
Results
The prevalence of sensory and motor impairment was 20% and 17.5%, respectively. Vinca-alkaloid exposure was associated with an increased risk of motor impairment (adjusted odds ratio [OR]=1.66; 95% confidence interval [CI], 1.04–2.64) without evidence for a dose response. Platinum exposure was associated with increased risk of sensory impairment (adjusted OR=1.62; 95% CI, .97–2.72) without evidence of a dose response. Sensory impairment was associated with poor endurance (OR=1.99; 95% CI, .99–4.0) and mobility (OR=1.65; 95% CI, .96–2.83).
Conclusions
Vincristine and cisplatin exposure may increase risk for long-term motor and sensory impairment, respectively. Survivors with sensory impairment are at increased risk for functional performance limitations.Disponible en ligne : Oui En ligne : https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/journal/a [...] Permalink : https://bib.vinci.be/opac_css/index.php?lvl=notice_display&id=117549
in Archives of Physical Medicine and Rehabilitation > 2013/8 (2013) . - pp. 1451-1457[article] Chemotherapy-Related Neuropathic Symptoms and Functional Impairment in Adult Survivors of Extracranial Solid Tumors of Childhood: Results From the St. Jude Lifetime Cohort Study [Article] / Kirsten Ness ; Kendra Jones ; Webb Smith ; [et al.] . - pp. 1451-1457.
Langues : Anglais (eng)
in Archives of Physical Medicine and Rehabilitation > 2013/8 (2013) . - pp. 1451-1457
Descripteurs : HE Vinci
Rééducation et réadaptation ; TumeursMots-clés : Cisplatin Cisplatine Neoplasms Peripheral nervous system diseases Neuropathies périphériques Vincristine Résumé : Objectives
To ascertain prevalence of peripheral sensory and motor neuropathy, and to evaluate impairments in relation to function.
Design
St. Jude Lifetime Cohort Study, a clinical follow-up study designed to evaluate adverse late effects in adult survivors of childhood cancer.
Setting
A children's research hospital.
Participants
Eligibility required treatment for an extracranial solid malignancy between 1962 and 2002, age ≥18 years, ≥10 years postdiagnosis, and no history of cranial radiation. Survivors (N=531) were included in the evaluation with a median age of 32 years and a median time from diagnosis of 25 years.
Interventions
Not applicable.
Main Outcome Measures
Primary exposure measures were cumulative doses of vinca-alkaloid and platinum-based chemotherapies. Survivors with scores ≥1 on the sensory subscale of the Modified Total Neuropathy Score were classified with prevalent sensory impairment. Those with sex-specific z scores of ≤−1.3 for dorsiflexion strength were classified with prevalent motor impairment. Participants completed the 6-minute walk test (endurance), the Timed Up & Go test (mobility), and the Sensory Organization Test (balance).
Results
The prevalence of sensory and motor impairment was 20% and 17.5%, respectively. Vinca-alkaloid exposure was associated with an increased risk of motor impairment (adjusted odds ratio [OR]=1.66; 95% confidence interval [CI], 1.04–2.64) without evidence for a dose response. Platinum exposure was associated with increased risk of sensory impairment (adjusted OR=1.62; 95% CI, .97–2.72) without evidence of a dose response. Sensory impairment was associated with poor endurance (OR=1.99; 95% CI, .99–4.0) and mobility (OR=1.65; 95% CI, .96–2.83).
Conclusions
Vincristine and cisplatin exposure may increase risk for long-term motor and sensory impairment, respectively. Survivors with sensory impairment are at increased risk for functional performance limitations.Disponible en ligne : Oui En ligne : https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/journal/a [...] Permalink : https://bib.vinci.be/opac_css/index.php?lvl=notice_display&id=117549
Titre : Delphi Study to Determine Rehabilitation Research Priorities for Older Adults With Cancer Type de document : Article Auteurs : Kathleen Doyle Lyons ; Mary Vining Radomski ; Catherine M. Alfano Article en page(s) : pp. 904-914 Langues : Anglais (eng) Descripteurs : HE Vinci
Consensus ; Rééducation et réadaptation ; Sujet âgé ; TumeursMots-clés : Aged Neoplasms Strategic planning Planification stratégique Résumé : Objective
To solicit expert opinions and develop consensus around the research that is needed to improve cancer rehabilitation for older adults.
Design
Delphi methods provided a structured process to elicit and prioritize research questions from national experts.
Setting
National, Web-based survey.
Participants
Members (N=32) of the American Congress of Rehabilitation Medicine completed at least 1 of 3 investigator-developed surveys.
Interventions
Not applicable.
Main Outcome Measures
In the first survey, participants identified up to 5 research questions that needed to be answered to improve cancer rehabilitation for older adults. In 2 subsequent surveys, participants viewed the compilation of questions, rated the importance of each question, and identified the 5 most important questions. This generated priority scores for each question. Consensus scores were created to describe the degree of agreement around the priority of each question.
Results
Highest priority research concerns the epidemiology and measurement of function and disability in older adult cancer survivors; the effects of cancer rehabilitation interventions on falls, disability, participation, survival, costs, quality of care, and health care utilization; and testing models of care that facilitate referrals from oncology to rehabilitation providers as part of coordinated, multicomponent care.
Conclusions
A multipronged approach is needed to fill these gaps, including targeted funding opportunities developed with an advisory panel of cancer rehabilitation experts, development of a research network to facilitate novel collaborations and grant proposals, and coordinated efforts of clinical groups to advocate for funding, practice change, and policy change.Disponible en ligne : Oui En ligne : https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/a [...] Permalink : https://bib.vinci.be/opac_css/index.php?lvl=notice_display&id=117743
in Archives of Physical Medicine and Rehabilitation > 2017/5 (2017) . - pp. 904-914[article] Delphi Study to Determine Rehabilitation Research Priorities for Older Adults With Cancer [Article] / Kathleen Doyle Lyons ; Mary Vining Radomski ; Catherine M. Alfano . - pp. 904-914.
Langues : Anglais (eng)
in Archives of Physical Medicine and Rehabilitation > 2017/5 (2017) . - pp. 904-914
Descripteurs : HE Vinci
Consensus ; Rééducation et réadaptation ; Sujet âgé ; TumeursMots-clés : Aged Neoplasms Strategic planning Planification stratégique Résumé : Objective
To solicit expert opinions and develop consensus around the research that is needed to improve cancer rehabilitation for older adults.
Design
Delphi methods provided a structured process to elicit and prioritize research questions from national experts.
Setting
National, Web-based survey.
Participants
Members (N=32) of the American Congress of Rehabilitation Medicine completed at least 1 of 3 investigator-developed surveys.
Interventions
Not applicable.
Main Outcome Measures
In the first survey, participants identified up to 5 research questions that needed to be answered to improve cancer rehabilitation for older adults. In 2 subsequent surveys, participants viewed the compilation of questions, rated the importance of each question, and identified the 5 most important questions. This generated priority scores for each question. Consensus scores were created to describe the degree of agreement around the priority of each question.
Results
Highest priority research concerns the epidemiology and measurement of function and disability in older adult cancer survivors; the effects of cancer rehabilitation interventions on falls, disability, participation, survival, costs, quality of care, and health care utilization; and testing models of care that facilitate referrals from oncology to rehabilitation providers as part of coordinated, multicomponent care.
Conclusions
A multipronged approach is needed to fill these gaps, including targeted funding opportunities developed with an advisory panel of cancer rehabilitation experts, development of a research network to facilitate novel collaborations and grant proposals, and coordinated efforts of clinical groups to advocate for funding, practice change, and policy change.Disponible en ligne : Oui En ligne : https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/a [...] Permalink : https://bib.vinci.be/opac_css/index.php?lvl=notice_display&id=117743 PermalinkPermalinkPermalinkPermalinkPermalinkPermalinkPermalinkPermalinkPermalinkPermalink
