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Auteur Ingeborg Dhooge |
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trié(s) par (Pertinence décroissant(e), Titre croissant(e)) Faire une suggestion Affiner la rechercheAntibiotiques en cas d’otite moyenne séromuqueuse chez l’enfant ? / Ingeborg Dhooge in Minerva, Vol. 16, n° 4 (Mai 2017)
Titre : Antibiotiques en cas d’otite moyenne séromuqueuse chez l’enfant ? Type de document : Article Auteurs : Ingeborg Dhooge ; I. Sintobin Année de publication : 2017 Article en page(s) : p. 88-91 Langues : Français (fre) Descripteurs : HE Vinci
Antibiotique ; Audition ; Enfant (6-12 ans) ; Otite ; Perforation ; PlaceboMots-clés : Drain transtympanique Otite séromuqueuse Perforation tympanique Résumé : Avant l’âge de 4 ans, 50 à 80% des enfants développent au moins un épisode d’OMS (1-3). L’OMS est la première cause d’intervention chirurgicale (drains transtympaniques, (adénoïdectomie) dans la petite enfance (1,4). Chez un enfant sur trois, on observe cependant une résolution spontanée dans les 3 mois après le diagnostic (5). La récidive est fréquente et elle survient, dans 50% des cas, au cours des 24 mois qui suivent la guérison (6). Certaines études suggèrent une étiologie bactérienne de l’OMS (7,8). C’est pour cette raison que plusieurs études ont recherché l’effet des antibiotiques pour le traitement de l’OMS. Disponible en ligne : Oui En ligne : http://www.minerva-ebm.be/FR/Article/2105 Permalink : https://bib.vinci.be/opac_css/index.php?lvl=notice_display&id=84387
in Minerva > Vol. 16, n° 4 (Mai 2017) . - p. 88-91[article]
Titre : Assessing the Clinical Value of Objective and Patient-Reported Audiovestibular Outcome Measures in the Risk Estimation of Systemic Cobalt Toxicity for Patients With a Metal-on-Metal Hip Implant Type de document : Article Auteurs : Laura Leyssens ; Bart Vinck ; Catherine Van Der Straeten ; Ingeborg Dhooge ; Floris L. Wuyts ; Philip Winnock de Grave ; Jan Van Melkebeek ; Filiep Bataillie ; Koen De Smet ; Ruth Van Hecke ; Maya Danneels ; Leen Maes Année de publication : 2022 Article en page(s) : p. 1502-1514 Note générale : DOI: 10.1097/AUD.0000000000001200 Langues : Anglais (eng) Descripteurs : HE Vinci
Hanche ; Metal ; Organes artificiels ; Ototoxicité ; Participation des patients ; VestibulométrieMots-clés : Cobalt, Implant, Metal-on-metal, Résumé : Objectives: Based on limited evidence from case reports and small cohort studies of metal-on-metal (MoM) hip implant patients with presumed systemic cobalt (Co) toxicity, and a few animal studies on Co-induced damage to the otovestibular system, it was hypothesised that Co exhibits an ototoxic potential alongside other systemic manifestations. Preliminary investigations from our research group in MoM patients confirmed this assumption for the auditory system, whereas no signs of Co-induced vestibular impairment were detected, and a clear dose-response relationship between the auditory function and the blood Co levels was lacking. Therefore, the current study aimed to extend and validate these findings in a larger sample of MoM patients and control subjects, to explore the potential clinical value of audiovestibular outcome measures in the risk estimation of systemic Co toxicity in this patient population.
Design: Fifty patients (32 to 68 years) with a primary unilateral/bilateral MoM hip implant were matched for age, gender, and noise exposure to 50 nonimplanted control subjects. Both groups underwent the same protocol, consisting of an objective auditory [i.e., conventional and high-frequency audiometry, transient-evoked and distortion (TEOAEs and DPOAEs), auditory brainstem responses] and vestibular (i.e., cervical and ocular vestibular evoked myogenic potentials, horizontal and vertical video head impulse tests) test battery, a questionnaire inquiring auditory, balance, and general neurological symptoms, and a blood sample collection to determine the plasma Co concentration.
Results: The auditory test battery presented consistently higher audiometric thresholds in the MoM patient group, with group differences ranging from 2.1 to 5.7 dB in the lower frequencies (0.25 to 6.0 kHz) and from 4.6 to 9.3 dB in the high frequencies (8.0 to 14.0 kHz). Group differences at high frequencies were statistically significant (p 0.01). Six patients had elevated Co levels according to our local institutional threshold (>4 or 5 [micro]g/l for unilateral or bilateral MoM hip implants, resp.), but their audiovestibular outcome measures did not differ significantly from those of the other patients.
Conclusions: Corresponding to our preliminary investigations, the results indicate possibly Co-induced (predominantly high-frequency) auditory impairment, probably triggered by toxic damage to the cochlear structures. However, the low mean difference values, the lack of group differences for the patient-reported outcome measures, and the lack of any relationship with the blood Co levels strongly reduce the clinical relevance of these findings. Therefore, the risk of Co-induced ototoxic impairment is considered to be clinically negligible for the majority of MoM hip implant patients, and the use of auditory tests in the risk estimation of systemic Co toxicity should be decided on a case-by-case basis.DOI : 10.1097/AUD.0000000000001200|1 Disponible en ligne : Oui En ligne : https://login.ezproxy.vinci.be/login?url=https://ovidsp.ovid.com/ovidweb.cgi?T=J [...] Permalink : https://bib.vinci.be/opac_css/index.php?lvl=notice_display&id=297650
in Ear and hearing > Vol. 43, n°5 (septembre-octobre 2022) . - p. 1502-1514[article]
Titre : Changes in Vestibular Function Following Pediatric Cochlear Implantation : a Prospective Study Type de document : Article Auteurs : Cleo Dhondt ; Leen Maes ; Saartje Vanaudenaerde ; Sarie Martens ; Lotte Rombaut ; Ruth Van Hecke ; Romain Valette ; Freya Swinnen ; Ingeborg Dhooge Année de publication : 2022 Article en page(s) : p. 620-630 Langues : Anglais (eng) Descripteurs : HE Vinci
Audiologie pédiatrique ; Enfant implanté ; Implants cochléaires ; VestibulométrieRésumé : Objectives: Given the close interconnection between the auditory and vestibular end organs, the increasingly broad application of (bilateral) cochlear implantation (CI) in children raises concern about its impact on the vestibular function. Unfortunately, literature on this matter is inconclusive and subject to several limitations. Therefore, this study aimed to elucidate the impact of pediatric CI on the vestibular function in a large sample of children, representative for the current CI population.
Design: Fifty hearing-impaired children followed in the Ghent University Hospital were included in this prospective study. Twenty-seven patients underwent unilateral CI, and 23 were bilaterally implanted (9 sequentially, 14 simultaneously), adding up to 73 implanted ears. Children's median age at first implantation was 29 (range 8 to 194) months. Vestibular assessment was scheduled on average 2.8 months (SD: 3.6) before and 4.6 (SD: 4.0) months after implantation and consisted of video Head Impulse Testing of the lateral semicircular canals, rotatory testing (0.16, 0.04, and 0.01 Hz) and cervical vestibular evoked myogenic potential (cVEMP) testing with bone conduction stimulation. Caloric testing was added in children older than 3 years of age.
Results: Overall, group analysis in our sample of 73 CI-ears did not reveal any significant impact on the vestibular function, except for a significantly shortened ipsilateral N1 latency of the cVEMP responses (p = 0.027) after CI. Complete ipsilateral loss of function after implantation was seen in 5% (3/54) of all CI-ears on the video head impulse testing, in 0% (0/10) on the caloric test and in 2% (1/52) on the cVEMP, notably all patients deafened by a congenital cytomegalovirus infection.
Conclusions: The impact of CI on the vestibular function in our dataset was limited. Therefore, the many advantages of simultaneous bilateral implantation may outweigh the risk for vestibular damage postoperatively. However, the impact on the vestibular function may be dependent on various factors (e.g., etiology of the hearing loss), and the clinical outcome is still difficult to predict. Vestibular assessment remains thus an important aspect in the pediatric CI population; first because the vestibular function should be considered in the decision-making process on (simultaneous or sequential bilateral) CI and second because it is essential to reveal a possible additional sensory deficit, allowing an opportunity for rehabilitation to improve the overall outcome of these children.DOI : 10.1097/AUD.0000000000001125|1 Disponible en ligne : Oui En ligne : https://login.ezproxy.vinci.be/login?url=https://ovidsp.ovid.com/ovidweb.cgi?T=J [...] Permalink : https://bib.vinci.be/opac_css/index.php?lvl=notice_display&id=293379
in Ear and hearing > Vol.43, n°2 (Mars-avril 2022) . - p. 620-630[article]
Titre : Congenital CMV-Associated Hearing Loss: Can Brain Imaging Predict Hearing Outcome? Type de document : Article Auteurs : Helen Van Hoecke ; Els De Leenheer ; An Boudewyns ; Ingeborg Dhooge Année de publication : 2021 Article en page(s) : p. 373-380 Langues : Anglais (eng) Descripteurs : HE Vinci
Cytomegalovirus ; Déficience auditive ; Imagerie par résonance magnétique ; Neuroimagerie ; Ondes ultrasonoresRésumé : Objectives: Congenital cytomegalovirus (cCMV) infection is the leading cause of nonhereditary sensorineural hearing loss in childhood and is also associated with CNS abnormalities. The main objective is to investigate the prognostic value of neonatal cranial ultrasound (cUS) and cranial magnetic resonance imaging (cMRI) in predicting long-term hearing outcome in a large cohort of cCMV-infected symptomatic and asymptomatic patients.
Design: Data were prospectively collected from a multicentre Flemish registry of children with cCMV infection born between 2007 and 2016. Neonatal cUS and cMRI scans were examined for lesions related to cCMV infection. Audiometric results at different time points were analyzed. The imaging and audiometric results were linked and diagnostic values of cUS and cMRI were calculated for the different hearing outcomes.
Results: We were able to include 411 cCMV patients, of whom 40% was considered symptomatic at birth. Cranial ultrasound abnormalities associated with cCMV infection were found in 76 children (22.2% of the cUS scans), whereas cMRI revealed abnormalities in 74 patients (26.9% of the cMRI scans). A significant relation could be found between the presence of cUS or cMRI abnormalities and hearing loss at baseline and last follow-up. Cranial ultrasound and cMRI findings were not significantly correlated with the development of delayed-onset hearing loss. Specificity and sensitivity of an abnormal cUS to predict hearing loss at final follow-up were 84% and 43%, respectively compared with 78% and 39% for cMRI. Normal cUS and cMRI findings have a negative predictive value of 91% and 92%, respectively, for the development of delayed-onset hearing loss.
Conclusions: Neuroimaging evidence of CNS involvement in the neonatal period is associated with the presence of hearing loss in children with a cCMV infection. Imaging abnormalities are not predictive for the development of delayed-onset hearing loss.DOI : 10.1097/AUD.0000000000000927|1 Disponible en ligne : Oui En ligne : https://login.ezproxy.vinci.be/login?url=https://ovidsp.ovid.com/ovidweb.cgi?T=J [...] Permalink : https://bib.vinci.be/opac_css/index.php?lvl=notice_display&id=269761
in Ear and hearing > Vol. 42, n°2 (Mars-Avril 2021) . - p. 373-380[article]
Titre : Listening Difficulties of Children With Cochlear Implants in Mainstream Secondary Education Type de document : Article Auteurs : Stefanie Krijger ; Martine Coenen ; Paul J. Govaerts ; Ingeborg Dhooge Année de publication : 2020 Article en page(s) : p. 1172-1186 Langues : Anglais (eng) Descripteurs : HE Vinci
Implants cochléaires ; Inclusion ; Perception auditive ; Performance scolaire
Autres descripteurs
Rehabilitation audiologique ; Suivi a long termeRésumé : Objectives: Previous research has shown that children with cochlear implants (CIs) encounter more communication difficulties than their normal-hearing (NH) peers in kindergarten and elementary schools. Yet, little is known about the potential listening difficulties that children with CIs may experience during secondary education. The aim of this study was to investigate the listening difficulties of children with a CI in mainstream secondary education and to compare these results to the difficulties of their NH peers and the difficulties observed by their teachers.
Design: The Dutch version of the Listening Inventory for Education Revised (LIFE-R) was administered to 19 children (mean age = 13 years 9 months; SD = 9 months) who received a CI early in life, to their NH classmates (n = 239), and to their teachers (n = 18). All participants were enrolled in mainstream secondary education in Flanders (first to fourth grades). The Listening Inventory for Secondary Education consists of 15 typical listening situations as experienced by students (LIFEstudent) during class activities (LIFEclass) and during social activities at school (LIFEsocial). The teachers completed a separate version of the Listening Inventory for Secondary Education (LIFEteacher) and Screening Instrument for Targeting Educational Risk.
Results: Participants with CIs reported significantly more listening difficulties than their NH peers. A regression model estimated that 75% of the participants with CIs were at risk of experiencing listening difficulties. The chances of experiencing listening difficulties were significantly higher in participants with CIs for 7 out of 15 listening situations. The 3 listening situations that had the highest chance of resulting in listening difficulties were (1) listening during group work, (2) listening to multimedia, and (3) listening in large-sized classrooms. Results of the teacher's questionnaires (LIFEteacher and Screening Instrument for Targeting Educational Risk) did not show a similar significant difference in listening difficulties between participants with a CI and their NH peers. According to teachers, NH participants even obtained significantly lower scores for staying on task and for participation in class than participants with a CI.
Conclusions: Although children with a CI seemingly fit in well in mainstream schools, they still experience significantly more listening difficulties than their NH peers. Low signal to noise ratios (SNRs), distortions of the speech signal (multimedia, reverberation), distance, lack of visual support, and directivity effects of the microphones were identified as difficulties for children with a CI in the classroom. As teachers may not always notice these listening difficulties, a list of practical recommendations was provided in this study, to raise awareness among teachers and to minimize the difficulties.Disponible en ligne : Oui En ligne : https://login.ezproxy.vinci.be/login?url=https://ovidsp.ovid.com/ovidweb.cgi?T=J [...] Permalink : https://bib.vinci.be/opac_css/index.php?lvl=notice_display&id=267999
in Ear and hearing > Vol. 41, n°5 (Septembre-octobre 2020) . - p. 1172-1186[article]
