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Auteur Angela C. Garinis |
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trié(s) par (Pertinence décroissant(e), Titre croissant(e)) Faire une suggestion Affiner la rechercheApplying U.S. national guidelines for ototoxicity monitoring in adult patients: perspectives on patient populations, service gaps, barriers and solutions. / Dawn Konrad-Martin ; Gayla L. Poling ; Angela C. Garinis ; Candice E. Ortiz ; Jennifer Hopper ; Keri O'Connell Bennett in International Journal of Audiology IJA, Vol. 57, S.4 (September 2018)
Titre : Applying U.S. national guidelines for ototoxicity monitoring in adult patients: perspectives on patient populations, service gaps, barriers and solutions. Type de document : Article Auteurs : Dawn Konrad-Martin ; Gayla L. Poling ; Angela C. Garinis ; Candice E. Ortiz ; Jennifer Hopper ; Keri O'Connell Bennett Année de publication : 2018 Article en page(s) : S3-S18 Langues : Anglais (eng) Descripteurs : HE Vinci
Audiologie clinique ; Déficience auditive ; OtotoxicitéRésumé : To promote establishment of effective ototoxicity monitoring programs (OMPs), this report reviews the U.S. national audiology guidelines in relation to “real world” OMP application. Background is provided on the mechanisms, risks and clinical presentation of hearing loss associated with major classes of ototoxic medications. Design: This is a non-systematic review using PubMed, national and international agency websites, personal communications between ototoxicity experts, and results of unpublished research. Examples are provided of OMPs in various healthcare settings within the U.S. civilian sector, Department of Defense (DoD), and Department of Veterans Affairs (VA). Study Sample: The five OMPs compared in this report represent a convenience sample of the programs with which the authors are affiliated. Their opinions were elicited via two semi-structured teleconferences on barriers and facilitators of OMP, followed by a self-administered questionnaire on OMP characteristics and practices, with responses synthesized herein. Preliminary results are provided from an ongoing VA clinical trial at one of these OMP sites. Participants were 40 VA patients who received cisplatin chemotherapy in 2014–2017. The study arms contrast access to care for OMP delivered on the treatment unit versus usual care as provided in the audiology clinic. Results: Protocols of the OMPs examined varied, reflecting their diverse settings. Service delivery concerns included baseline tests missed or completed after the initial treatment, and monitoring tests done infrequently or only after cessation of treatment. Perceived barriers involved logistics related to accessing and testing patients, such as a lack of processes to help patients enter programs, patients’ time and scheduling constraints, and inconvenient audiology clinic locations. Use of abbreviated or screening methods facilitated monitoring. Conclusions: The most effective OMPs integrated audiological management into care pathways of the clinical specialties that prescribe ototoxic medications. More OMP guidance is needed to inform evaluation schedules, outcome reporting, and determination of actionable ototoxic changes. Guidance is also lacking on the use of hearing conservation approaches suitable for the mass testing needed to support large-scale OMP efforts. Guideline adherence might improve with formal endorsement from organizations governing the medical specialty stakeholders in OMP such as oncologists, pulmonologists, infectious disease specialists, ototolaryngologists and pharmacists. Accès : Contactez la bibliothèque d'Ixelles si le lien vers la ressource électronique ne fonctionne plus Disponible en ligne : Non Permalink : https://bib.vinci.be/opac_css/index.php?lvl=notice_display&id=210465
in International Journal of Audiology IJA > Vol. 57, S.4 (September 2018) . - S3-S18[article]Exemplaires (1)
Cote Support Localisation Section Disponibilité International journal of audiology IJA. Vol. 57, S.4 (September 2018) Périodique papier Ixelles Rez Consultation sur place uniquement
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Titre : Automated Adaptive Wideband Acoustic Reflex Threshold Estimation in Normal-hearing Adults Type de document : Article Auteurs : Kim Schairer ; Daniel B. Putterman ; Douglas H. Keefe ; Dennis F. Fitzpatrick ; Angela C. Garinis ; Elizabeth R. Kolberg ; M. Patrick Feeney Année de publication : 2022 Article en page(s) : p. 370-378 Langues : Anglais (eng) Descripteurs : HE Vinci
Acoustique
Autres descripteurs
Immitance acoustique ; Reflexe de l'oreille moyenne ; Reflexion a large bandeRésumé : Objectives: Acoustic stapedius reflex threshold (ART) tests are included in a standard clinical acoustic immittance test battery as an objective cross-check with behavioral results and to help identify site of lesion. In traditional clinical test batteries, middle-ear admittance of a 226 Hz probe is estimated using ear-canal measurements in the presence of a reflex-activating stimulus. In the wideband (WB) acoustic immittance ART test used in this study, the pure-tone probe is replaced by a WB probe stimulus and changes in absorbed power are estimated using ear-canal measurements in the presence of the activator. The ART is defined as the lowest level at which a criterion change in admittance (clinical) or absorbed power (WB) is observed in the presence of the activator. In the present study, ARTs were obtained in adults with normal hearing using the clinical, manual method and with a new WB automated adaptive threshold detection method. It was hypothesized that the WB test would result in lower ARTs than the clinical test because reflex-related changes in power absorbance could be observed across multiple frequency bands in the WB test compared with a single frequency in the traditional test.
Design: Data were collected in a prospective research design. ARTs were obtained in ipsilateral and contralateral conditions using 500, 1000, 2000 Hz, and broadband noise (BBN) activators on a clinical system and on an experimental WB system. The bandwidth of the BBN activator was 125 to 4000 Hz on the clinical system and 200 to 8000 Hz on the wideband system. ARTs were estimated at both tympanometric peak pressure (TPP) and ambient pressure on the WB system. Data were collected in both ears of 39 adults (21 males) of mean age 47.7 years (range 23-72 years). Differences in ARTs among the three threshold estimation methods (clinical, WB at TPP, WB at ambient) were examined using the general linear model repeated measures test in SPSS. Post-hoc pairwise comparisons were completed with Bonferroni correction for multiple comparisons. Statistical significance was defined as p
Results: ARTs obtained on the WB system at TPP and ambient pressure were significantly lower than obtained on the clinical system. ARTs obtained on the WB system at TPP were significantly higher than at ambient pressure in the 500 and 2000 Hz ipsilateral conditions.
Conclusions: WB automated adaptive ARTs in normal-hearing adults were lower than for clinical methods when measured at TPP and ambient pressure. Lower presentation levels required to estimate ART in the WB test may be more tolerable to patients. Patients with ARTs that are not present at the maximum level of a traditional reflex test may have present ARTs with a WB ART test, which may reduce the need to refer for additional testing for possible retrocochlear involvement. Automation of the test may allow clinicians more time to attend to the other requisite tasks of a hearing evaluation and make the system useful for telehealth applications.DOI : 10.1097/AUD.0000000000001102|1 Disponible en ligne : Oui En ligne : https://login.ezproxy.vinci.be/login?url=https://ovidsp.ovid.com/ovidweb.cgi?T=J [...] Permalink : https://bib.vinci.be/opac_css/index.php?lvl=notice_display&id=292896
in Ear and hearing > Vol.43, n°2 (Mars-avril 2022) . - p. 370-378[article]
Titre : Effects of Otosclerosis on Middle Ear Function Assessed With Wideband Absorbance and Absorbed Power Type de document : Article Auteurs : M. Patrick Feeney ; Douglas H. Keefe ; Lisa L. Hunter ; Dennis F. Fitzpatrick ; Daniel B. Putterman ; Angela C. Garinis Année de publication : 2021 Article en page(s) : p. 547-557 Langues : Anglais (eng) Descripteurs : Autres descripteurs
Otosclerose ; Reflectance acoustique
HE Vinci
Absorbance acoustique ; Oreille moyenne ; Tympanométrie ; Wideband absorbance (WBA)Résumé : Objective: Wideband absorbance and absorbed power were evaluated in a group of subjects with surgically confirmed otosclerosis (Oto group), mean age 51.6 years. This is the first use of absorbed power in the assessment of middle ear disorders. Results were compared with control data from two groups of adults, one with normal hearing (NH group) mean age of 31 years, and one that was age- and sex-matched with the Oto group and had sensorineural hearing loss (SNHL group). The goal was to assess group differences using absorbance and absorbed power, to determine test performance in detecting otosclerosis, and to evaluate preoperative and postoperative test results.
Design: Audiometric and wideband tests were performed over frequencies up to 8 kHz. The three groups were compared on wideband tests using analysis of variance to assess group mean differences. Receiver operating characteristic (ROC) curve analysis was also used to assess test accuracy at classifying ears as belonging to the Oto or control groups using the area under the ROC curve (AUC). A longitudinal design was used to compare preoperative and postoperative results at 3 and 6 months.
Results: There were significant mean differences in the wideband parameters between the Oto and control groups with generally lower absorbance and absorbed power for the Oto group at ambient and tympanometric peak pressure (TPP) depending on frequency. The SNHL group had more significant differences with the Oto group than did the NH group in the high frequencies for absorbed power at ambient pressure and tympanometric absorbed power at TPP, as well as for the tympanometric tails. The greatest accuracy for classifying ears as being in the Oto group or a control group was for absorbed power at ambient pressure at 0.71 kHz with an AUC of 0.81 comparing the Oto and NH groups. The greatest accuracy for an absorbance measure was for the comparison between the Oto and NH groups for the peak-to-negative tail condition with an AUC of 0.78. In contrast, the accuracy for classifying ears into the control or Oto groups for static acoustic admittance at 226 Hz was near chance performance, which is consistent with previous findings. There were significant mean differences between preoperative and postoperative tests for absorbance and absorbed power.
Conclusions: Consistent with previous studies, wideband absorbance showed better sensitivity for detecting the effects of otosclerosis on middle ear function than static acoustic admittance at 226 Hz. This study showed that wideband absorbed power is similarly sensitive and may perform even better in some instances than absorbance at classifying ears as having otosclerosis. The use of a group that was age- and sex-matched to the Oto group generally resulted in greater differences between groups in the high frequencies for absorbed power, suggesting that age-related norms in adults may be useful for the wideband clinical applications. Absorbance and absorbed power appear useful for monitoring changes in middle ear function following surgery for otosclerosis.DOI : 10.1097/AUD.0000000000000968|1 Disponible en ligne : Oui En ligne : https://login.ezproxy.vinci.be/login?url=https://ovidsp.ovid.com/ovidweb.cgi?T=J [...] Permalink : https://bib.vinci.be/opac_css/index.php?lvl=notice_display&id=273194
in Ear and hearing > Vol. 42, n°3 (Mai- Juin 2021) . - p. 547-557[article]
Titre : Monitoring neonates for ototoxicity Type de document : Article Auteurs : Angela C. Garinis ; Alison Kemph ; Anne Marie Tharpe ; Joern-Hendrik Weitkamp ; Cynthia McEvoy ; Peter S. Steyger Année de publication : 2018 Article en page(s) : p. S54-61 Langues : Anglais (eng) Descripteurs : HE Vinci
Anatomie ; Compétence du nouveau-né ; Dépistage auditif du nouveau-néRésumé : Neonates admitted to the neonatal intensive care unit (NICU) are at greater risk of permanent hearing loss compared to infants in well mother and baby units. Several factors have been associated with this increased prevalence of hearing loss, including congenital infections (e.g. cytomegalovirus or syphilis), ototoxic drugs (such as aminoglycoside or glycopeptide antibiotics), low birth weight, hypoxia and length of stay. The aetiology of this increased prevalence of hearing loss remains poorly understood. Design: Here we review current practice and discuss the feasibility of designing improved ototoxicity screening and monitoring protocols to better identify acquired, drug-induced hearing loss in NICU neonates. Study sample: A review of published literature. Conclusions: We conclude that current audiological screening or monitoring protocols for neonates are not designed to adequately detect early onset of ototoxicity. This paper offers a detailed review of evidence-based research, and offers recommendations for developing and implementing an ototoxicity monitoring protocol for young infants, before and after discharge from the hospital. Accès : Contactez la bibliothèque d'Ixelles si le lien vers la ressource électronique ne fonctionne plus Disponible en ligne : Non Permalink : https://bib.vinci.be/opac_css/index.php?lvl=notice_display&id=210470
in International Journal of Audiology IJA > Vol. 57, S.4 (September 2018) . - p. S54-61[article]Exemplaires (1)
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Titre : Ototoxicity monitoring through the eyes of the treating physician: Perspectives from pulmonology and medical oncology Type de document : Article Auteurs : Angela C. Garinis ; Alexandra Cornell ; Gopal Allada ; Kevin P. Fennelly ; Ronald J. Maggiore ; Dawn Konrad-Martin Année de publication : 2018 Article en page(s) : p. S42-47 Langues : Anglais (eng) Descripteurs : HE Vinci
Audiologie clinique ; Chimiothérapie ; Evaluation auditive ; Oncologie médicale ; OtotoxicitéRésumé : Integrating audiological management into the care pathways of clinical specialties that prescribe ototoxic medications for essential, often life-preserving medical care that is critical for early hearing loss identification and remediation. Research shows that successful implementation of a new health service or intervention requires alignment of goals among provider groups, institutional leadership and patients. Thoughtful consideration of the physician’s viewpoints about ototoxicity and its implications for treatment planning is, therefore, important for the implementation and enduring success of an ototoxicity monitoring programme (OMP). Design: This discussion paper uses qualitative methods to explore the perspectives of four physicians on OMP provision in their patient populations. Study sample: Three pulmonologists and one oncologist completed the written survey or survey-based interview described in this report. Results: Each physician indicated that (i) ototoxicity is a potential problem for their patients; (ii) monitoring hearing is important to ensure good quality of life among their patients and (iii) treatment modification would be considered if an alternative treatment option were available. The physicians differed in their approaches to ototoxicity monitoring, from routine referrals to audiology, to relying on patient self-referral. Conclusion: Physician provider input is needed to optimise monitoring schedules and OMP care coordination with audiology. Accès : Contactez la bibliothèque d'Ixelles si le lien vers la ressource électronique ne fonctionne plus Disponible en ligne : Non Permalink : https://bib.vinci.be/opac_css/index.php?lvl=notice_display&id=210468
in International Journal of Audiology IJA > Vol. 57, S.4 (September 2018) . - p. S42-47[article]Exemplaires (1)
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