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Titre : | Honey in the management of side effects of radiotherapy- or radio/chemotherapy-induced oral mucositis. A systematic review (2019) |
Auteurs : | Karsten Münstedt ; Felix Momm ; Jutta Hübnef |
Type de document : | Article |
Dans : | Complementary Therapies in Clinical Practice (Vol. 34, February 2019) |
Article en page(s) : | p. 145-152 |
Note générale : | https://doi.org/10.1016/j.ctcp.2018.11.016 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Chimiothérapie ; Miel ; Radiothérapie ; Stomatite ; Thérapies complémentaires |
Résumé : |
Background
and purpose: In spite of several trials, systematic reviews and meta-analyses, honey is not considered as a viable candidate for the prophylaxis and treatment of radiotherapy-induced oral mucositis in the practice guidelines for supportive care. The purpose of this study was to analyse the value of honey in this treatment situation based on randomized trials acknowledging the fact that manuka honey which is used in some trials distinguishes itself from other honey due to the presence of methylglyoxal. Methods On the basis of a literature search, we identified and analysed 17 randomized trials on the topic. Participants in these trials received radiotherapy or a combination of radiotherapy and chemotherapy for head and neck cancer. Results Studies using manuka honey found little rationale for the medicinal use of honey (n = 4) in this field, whereas trials using conventional honey presented data on its usefulness (n = 13). Thus, the type of honey may explain the divergent results of trials in this area. Conclusion Conventional honey is likely to be effective in the prophylaxis and treatment of radiation- and chemoradiation-induced oral mucositis. |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/article/abs/pii/S1744388118305462 |
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