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Titre : | # Vitamin D: an overview of its role in skeletal muscle physiology in children and adolescents (2012) |
Auteurs : | Tom Hazell, Auteur ; Jason Deguire, Auteur ; Hope Weiler, Auteur |
Type de document : | Article |
Dans : | Nutrition reviews (70, n° 9, 2012) |
Article en page(s) : | 520-533 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Adolescent ; Enfant (6-12 ans) ; Muscles ; Vitamine D |
Résumé : | Many children may have insufficient serum concentrations of vitamin D, which could prevent optimal muscle development and function. Vitamin D deficiency in animal models results in negative effects on muscle fiber structure and calcium/phosphorus handling, suggesting an integral role of vitamin D in skeletal muscle function. While there is a dearth of data in humans, the available evidence demonstrates a positive association between vitamin D status and muscle function. This review focuses on the important role of vitamin D in muscle function in children and adolescents who live in North American regions where exposure to ultraviolet B radiation is limited and who are thus at increased risk for vitamin D insufficiency. The effects of vitamin D on muscle cell proliferation and differentiation, muscle fiber structure, and calcium and phosphorus handling are discussed. Moreover, the roles of vitamin D and the vitamin D receptor and their genomic and nongenomic actions in muscle function are explored in depth. Future research should aim to establish a vitamin D status consistent with optimal musculoskeletal development and function in young children. |
Disponible en ligne : | Non |
Exemplaires (1)
Cote | Support | Localisation | Section | Disponibilité |
---|---|---|---|---|
REV | Périodique papier | Woluwe | Espace revues | Consultation sur place uniquement Exclu du prêt |