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Titre : | FDG-guided excision of peripheral non-palpable lymph nodes in the axilla with suspected malignancy (2024) |
Titre original: | Excision guidée par FDG des ganglions lymphatiques non palpables de laisselle avec suspicion de malignité |
Auteurs : | B. Ilhan, Auteur ; A. Kut, Auteur ; S. Bademler, Auteur ; S. Kilic, Auteur ; F. Yanar, Auteur ; H. Karanlik, Auteur |
Type de document : | Article |
Dans : | Médecine nucléaire (Vol 48, n°1, février 2024) |
Article en page(s) : | 1-7 |
Note générale : | Doi : 10.1016/j.mednuc.2023.08.002 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Lymphadénectomie ; Ultrason |
Mots-clés: | Absorption du FDG ; Biopsie radioguidée |
Résumé : |
Objective
To define the feasibility of 18F-fluorodeoxyglucose (FDG) uptake tracing in the excision of potentially malignant non-palpable lymph nodes (NLN), especially in the axilla. Materials and methods Findings of 493 peripheral lymph node (LN) excisions were examined in the study. Three hundred seventy-eight LNs were palpable and the remaining 115 LNs were non-palpable. The excised NLNs were analyzed in two groups, NLNs excised based on the anatomical descriptions of imaging methods (n =62), image-guided NLN excisions (n =53). Among the image-guided excisions, 27 NLNs were excised using real-time ultrasound (US) guidance, and 26 NLNs were excised using FDG uptake tracing. Results Image-guided excisions provided better diagnostic accuracy for potentially malignant NLNs compared with excisions made located based on imaging descriptions (P =0.029). In these image-guided NLN excisions, the FDG uptake-trace method combined with positron emission tomography-computed tomography (PET-CT) was more successful in detecting malignant NLNs compared with US guidance (P =0.04). NLN excisions based on FDG uptake were completed in a shorter time than both excisions with US guidance (P =0.006) and excisions made locating based on imaging definitions (P =0.001). Conclusion Potentially malignant NLN excisions can be challenging for surgeons, and can result in prolonged surgical time. It may be extrapolated from our study that anatomy and metabolism-based LN excision guidance using information obtained in PET-CT and following FDG uptake tracing may improve the accuracy of histologic examinations, and thus increase the probability of achieving a correct diagnosis. |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.em-premium.com/article/1647769 |