| Titre : | Plan quality score to evaluate the dwell time deviation restricted inverse planning by simulated annealing and graphically optimized treatment plans for template based interstitial brachytherapy (2023) |
| Auteurs : | K. Mondal ; Muskaan, ; A. Mourya ; S. Choudhary ; A. Mandal ; A. Singh ; L.M. Aggarwal |
| Type de document : | Article |
| Dans : | Cancer/Radiothérapie (Vol. 27, n° 3, Mai 2023) |
| Article en page(s) : | p. 196-205 |
| Note générale : | https://doi.org/10.1016/j.canrad.2022.10.006 |
| Langues: | Anglais |
| Descripteurs : |
HE Vinci Curiethérapie ; Dose de radiation ; Planification de radiothérapie assistée par ordinateur ; Radiothérapie ; Tumeurs du col de l'utérus |
| Mots-clés: | Radiométrie ; Optimisation inverse ; Score de qualité du plan ; Curiethérapie interstitielle ; Modèle interstitiel périnéal ; Restriction du temps de séjour |
| Résumé : |
Purpose
To evaluate the impact of dwell time deviation constraint (DTDC) on the quality of IPSA-optimized treatment plans in comparison with graphical plans using plan quality scores (PQS). Material and methods Seventy optimized plans (graphical & IPSA with different DTDC values) of ten cervical cancer patients were generated. Various DVH parameters like D90, V100, V150, V200, V300 were compared to evaluate the impact of DTDC on target coverage and high dose regions inside target for different plans. Similarly, for the OAR dose, values of D2cc were compared. Various planning parameters like CI, COIN, DHI, DNR, ODI, EI and gain factor (GF) for different OARs were calculated. Based on these indices a plan quality score (PQS) was formulated and calculated. PQS values were used to see the impact of DTDC on plan quality of IPSA in comparison with dosimetric quality of graphical plan. Results We have found that target coverage is similar for IPSA and graphically optimized treatment plans. However, dose homogeneity was improved in IPSA compared to graphical optimization whereas conformality was better in graphically optimized plans. OAR dose was less in IPSA plans. High-dose regions inside the target were also reduced in IPSA comparatively. However, IPSA plans optimized with various values of DTDC did not necessarily reduce high-dose regions beyond 0.6. Plan quality scores (PQS) were 6.31, 6.31, 6.34, and 6.17 for the graphically optimized plan, IPSA with DTDC values of 0.0, 0.4, and 1.0 respectively. Conclusion We found that IPSA is dosimetrically advantageous over graphical optimization. IPSA with a DTDC value of 0.4 improved overall plan quality. However, DTDC value beyond 0.6 produces dosimetrically sub-optimal plans hence the use of DTDC should be very selective and limited. |
| Disponible en ligne : | Oui |
| En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/article/pii/S1278321823000586 |
Bibliothèques HE Vinci
