| Titre : | Effects of dietary polyphenols in the glycemic, renal, inflammatory, and oxidative stress biomarkers in diabetic nephropathy: a systematic review with meta-analysis of randomized controlled trials (2022) |
| Auteurs : | Mateus de Lima Macena ; Lara Fernanda da Silva Nunes ; Andreza Ferreira da Silva ; Isabele Rejane Oliveira Maranhão Pureza ; Dafiny Rodrigues Silva Praxedes ; Juliana Célia de Farias Santos ; Nassib Bezerra Bueno |
| Type de document : | Article |
| Dans : | Nutrition reviews (Vol. 80, n° 12, December 2022) |
| Article en page(s) : | p. 2237-2259 |
| Note générale : | https://doi.org/10.1093/nutrit/nuac035 |
| Langues: | Anglais |
| Descripteurs : |
HE Vinci Complications du diabète ; Curcumine ; Défaillance rénale chronique ; Diabète ; Glycémie ; Hémoglobine A glycosylée ; Isoflavones ; Marqueurs biologiques ; Nephropathie diabétique ; Protéine C-réactive ; Protéines de soja ; Proteinurie ; Resvératrol ; Stress oxydatif |
| Résumé : |
Context: Polyphenols have antioxidant, anti-inflammatory, and anti-glycation properties.
Objective: To assess the effects of dietary polyphenols, from food sources or supplements, on the anthropometric, glycemic, renal, inflammatory, and oxidative stress markers in adults with diabetic nephropathy (DN). Data Sources: Systematic searches for randomized clinical trials were performed in MEDLINE, Embase, CENTRAL, Web of Science, LILACS, SciELO, opengrey.eu, and ClinicalTrials.gov databases until December 2021. Data Extraction: Studies with adults with DN were included. Random-effects meta-analyses were conducted. Risk of bias of the studies and Grading of Recommendations, Assessment, Development, and Evaluation assessment were carried out. Conclusions: There is a clinically modest effect of dietary polyphenols intervention in HbA1c, proteinuria, GFR, MDA, and C-reactive protein levels in patients with DN. It is impossible to establish clinical recommendations, because the evidence was of' low or very-low quality and because of the heterogeneity of types and dose regimens used in the studies. |
| Disponible en ligne : | Oui |
| En ligne : | https://login.ezproxy.vinci.be/login?url=https://academic.oup.com/nutritionreviews/article/80/12/2237/6589992 |
Bibliothèques HE Vinci
