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Titre : | The value of 99mTc-MIBI scan in the detection of malignancy potential of hypermetabolic thyroid incidentalomas of 18F-FDG PET/CT (2022) |
Auteurs : | G. Tatar ; G. Alçın ; Ö. Erol Fenercioğlu ; E. Beyhan ; H.Y. Barut ; N. Ergül ; T.F. Çermik |
Type de document : | Article |
Dans : | Médecine nucléaire (vol. 46, n°3, Juin 2022) |
Article en page(s) : | p. 139-145 |
Note générale : | https://doi.org/10.1016/j.mednuc.2022.01.131 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Fluorodésoxyglucose F18 ; Nodule thyroidien ; Tomographie par émission de positons |
Mots-clés: | TEP/CT au F-FDG ; Tc-99m ; Analyse MIBI ; Nodules thyroïdiens accidentels |
Résumé : | Aim of the study Increasingly use of PET/CT leads to discovery of incidental findings. Hypermetabolic thyroid nodules are one of the unexpected lesions in PET/CT imaging with an increased risk of thyroid cancers. Our study aims to determine the malignant potential of incidentally detected 18F-FDG avid thyroid nodules by using Tc-99m MIBI imaging. Materials and methods PET/CT scans were performed for nonthyroidal purposes and were evaluated for the presence of hypermetabolic thyroid nodules. Tc-99m MIBI scans and ultrasonography-guided fine needle aspiration biopsies were subsequently performed for all patients. Results Primary thyroid malignancies were identified in 25% of patients with increased focal FDG uptake at definitive diagnosis. Among the patients with FDG avid thyroid nodules, Tc-99m MIBI scan showed true-positive results in all thyroid carcinomas (n:7) with a 36.3% (4/11) false-positivity rate. In three patients with indeterminate cytology results, Tc-99m MIBI scan findings were also negative. The sensitivity, specificity, positive predictive value of Tc-99m MIBI scan in predicting the malignancy of FDG-positive thyroid nodules were 100%, 77%, 63.6%, respectively. Conclusion The implementation of 99mTc-MIBI scan performed by dual phase and SPECT/CT modality might be a helpful cost-effective approach in addition to FNAB in patients with 18F-FDG-positive thyroid nodules and indeterminate cytology to improve the patients? prognosis and reduce unnecessary thyroid operations with associated use of FNAB. |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.em-premium.com/article/1524586 |