| Titre : | Optimal radiotherapy after breast-conserving surgery for early breast cancer: A network meta-analysis of 23,418 patients (2022) |
| Auteurs : | X. Chen ; T.-X. Yang ; Y.-X. Xia ; Q. Shen ; Y. Hou ; L. Wang ; L. Li ; L. Chang ; W.-H. Li |
| Type de document : | Article |
| Dans : | Cancer/Radiothérapie (vol. 26, no. 8, Novembre 2022) |
| Article en page(s) : | p. 1054-1063 |
| Note générale : | https://doi-org.ezproxy.vinci.be/10.1016/j.canrad.2022.04.003 |
| Langues: | Anglais |
| Descripteurs : |
HE Vinci Radiothérapie ; Tumeurs du sein |
| Mots-clés: | Radiothérapie fractionnée ; Radiothérapie conventionnelle fractionnée ; Irradiation partielle du sein ; Chirurgie de conservation du sien |
| Résumé : | Purpose In order to explore whether partial breast irradiation can replace hypofractionated whole breast irradiation and whether the former two are superior to conventional fractionated whole breast irradiation, we conducted a network meta-analysis based on the data from the latest randomized controlled trials to evaluate the efficacy of these radiotherapy modalities. Material and methods Data from eligible studies were analyzed to determine the published events for ipsilateral breast tumor recurrence, distant metastasis, total deaths, and non-breast cancer-related deaths. In the case of low or high heterogeneity, the fixed-effect or random-effect model was used for statistical analysis respectively. NMA was performed by using the node-splitting model for two-category data among three radiotherapies based on a Bayesian method. Results A total of 23,418 patients were included in 16 studies. For ipsilateral breast tumor recurrence, both pairwise (OR=1.9; CI95%: 1.2 -2.8; p |
| Disponible en ligne : | Oui |
| En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/article/pii/S1278321822000865 |
Bibliothèques HE Vinci
