Login
Communauté Vinci
Extérieur
Si votre nom d'utilisateur ne se termine pas par @vinci.be ou @student.vinci.be, utilisez le formulaire ci-dessous pour accéder à votre compte de lecteur.
Titre : | Radiotherapy for hypopharynx cancers (2022) |
Auteurs : | Yoann Pointreau ; J. Biau ; N. Delaby ; J. Thariat ; M. Lapeyre |
Type de document : | Article |
Dans : | Cancer/Radiothérapie (vol. 26, n° 1-2, février-avril 2022) |
Article en page(s) : | p. 199-205 |
Note générale : | https://doi-org.ezproxy.vinci.be/10.1016/j.canrad.2021.10.006 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Dose de radiation ; Oncologie médicale ; Radiothérapie conformationnelle ; Recommandations comme sujet ; Relation dose-effet des radiations |
Résumé : | We present the update of the recommendations of the French society of oncological radiotherapy on radiotherapy for hypopharynx. Intensity-modulated radiotherapy is the gold standard treatment for hypopharynx cancers. Early T1 and T2 tumors could be treated by exclusive radiotherapy or surgery followed by postoperative radiotherapy in case of high recurrence risk. For locally advanced tumours requiring total pharyngolaryngectomy (T2 or T3) or with significant lymph nodes involvement, induction chemotherapy followed by exclusive radiotherapy or concurrent chemoradiotherapy were possible. For T4 tumour, surgery must be proposed. The treatment of lymph nodes is based on initial primary tumour treatment. In non-surgical procedure, for 35 fractions, curative dose is 70 Gy (2 Gy per fraction) and prophylactic dose are 50 to 56 Gy (2 Gy per fraction in case of sequential radiotherapy or 1.6 Gy in case of integrated simultaneous boost) radiotherapy; for 33 fractions, curative dose is 69.96 Gy (2.12 Gy per fraction) and prophylactic dose is 52.8 Gy (1.6 Gy per fraction in integrated simultaneous boost radiotherapy or 54 Gy in 1.64 Gy per fraction); for 30 fractions, curative dose is 66 Gy (2.2 Gy per fraction) and prophylactic dose is 54 Gy (1.8 Gy per fraction in integrated simultaneous boost radiotherapy). Doses over 2 Gy per fraction could be done when chemotherapy is not used regarding potential larynx toxicity. Postoperatively, radiotherapy is used in locally advanced cancer with dose levels based on pathologic criteria, 60 to 66 Gy for R1 resection and 54 to 60 Gy for complete resection in bed tumour; 50 to 66 Gy in lymph nodes areas regarding extracapsular spread. Volume delineation were based on guidelines cited in this article. |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/article/pii/S1278321821002705 |