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Titre : | A Broadly Applicable Method for Characterizing the Slope of the Electrically Evoked Compound Action Potential Amplitude Growth Function (2022) |
Auteurs : | Jeffrey Skidmore ; Dyan Ramekers ; Deborah Colesa ; Kara Schvartz-Leysac ; Bryan E. Pfingst ; Shuman He |
Type de document : | Article |
Dans : | Ear and hearing (Vol.43, n°1, Janvier-février 2022) |
Article en page(s) : | p. 150-164 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Implants cochléaires ; Nerf vestibulocochléaireAutres descripteurs Modulation d'amplitude ; Potentiels évoqués a action composée (eCAP) |
Résumé : | Amplitudes of electrically evoked compound action potentials (eCAPs) as a function of the stimulation level constitute the eCAP amplitude growth function (AGF). The slope of the eCAP AGF (i.e., rate of growth of eCAP amplitude as a function of stimulation level), recorded from subjects with cochlear implants (CIs), has been widely used as an indicator of survival of cochlear nerve fibers. However, substantial variation in the approach used to calculate the slope of the eCAP AGF makes it difficult to compare results across studies. In this study, we developed an improved slope-fitting method by addressing the limitations of previously used approaches and ensuring its application for the estimation of the maximum slopes of the eCAP AGFs recorded in both animal models and human listeners with various etiologies. |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://journals.lww.com/ear-hearing/fulltext/2022/01000/a_broadly_applicable_method_for_characterizing_the.15.aspx |