| Titre : | Role of microbiota-gut-brain axis dysfunctions induced by infections in the onset of anorexia nervosa (2022) |
| Auteurs : | Marie Galmiche ; Najate Achamrah ; Pierre Déchelotte ; David Ribet ; Jonathan Breton |
| Type de document : | Article |
| Dans : | Nutrition reviews (Vol. 80, n°3, March 2022) |
| Article en page(s) : | p. 381-391 |
| Note générale : | https://doi.org/10.1093/nutrit/nuab030 |
| Langues: | Anglais |
| Descripteurs : |
HE Vinci Anorexie mentale ; Anxiété ; Dysbiose ; Infections ; Microbiome gastro-intestinal ; Régime alimentaire ; Troubles anxieux ; Troubles de l'alimentation |
| Résumé : | Anorexia nervosa (AN) is an eating disorder characterized by low food intake, severe body weight loss, intense fear of gaining weight, and dysmorphophobia. This chronic disease is associated with both psychiatric and somatic comorbidities. Over the years, clinical studies have accumulated evidence that viral or bacterial infections may promote the onset of eating disorders such as AN. This review aims to describe how infections and the subsequent immune responses affect food intake regulation in the short term and also how these processes may lead to long-term intestinal disorders, including gut barrier disruption and gut microbiota dysbiosis, even after the clearance of the pathogens. We discuss in particular how infection-mediated intestinal dysbiosis may promote the onset of several AN symptoms and comorbidities, including appetite dysregulation, functional gastrointestinal disorders, and mood disorders. |
| Disponible en ligne : | Oui |
| En ligne : | https://login.ezproxy.vinci.be/login?url=https://academic.oup.com/nutritionreviews/article/80/3/381/6278454 |
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