Login
Communauté Vinci
Extérieur
Si votre nom d'utilisateur ne se termine pas par @vinci.be ou @student.vinci.be, utilisez le formulaire ci-dessous pour accéder à votre compte de lecteur.
Titre : | Aerobic, resistance and combined exercise training for patients with amyotrophic lateral sclerosis: a systematic review and meta-analysis (2021) |
Auteurs : | Masoud Rahmati ; Fatemeh Malakoutinia |
Type de document : | Article |
Dans : | Physiotherapy (Vol. 113, 2021) |
Article en page(s) : | p. 12-28 |
Note générale : | https://doi.org/10.1016/j.physio.2021.04.005 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Exercice physique ; Méta-analyse ; Revue systématique ; Sclérose latérale amyotrophique (SLA) |
Résumé : |
Objective
The aim of this systematic review and meta-analysis was to assess the effect of aerobic, resistance and combined exercise training in patients with ALS. Data source A comprehensive systematic search of CENTRAL, CINAHL, SPORTDiscuss, Embase, Scopus, ProQuest was performed from inception to February 2021. Eligibility criteria The systematic review included all studies that examined the effect of exercise training in ALS patients. Meta-analysis was also carried out on randomized controlled trials (RCTs). Data extraction and data synthesis Data related to primary outcomes (functional ability, respiratory function, fatigue, pain, quality of life, upper-body strength, lower-body strength and Vo2peak) and secondary outcomes (adverse events and feasibility of exercises) was extracted from all studies and systematically reviewed. Results 16 trials including 532 patients met the inclusion criteria; of these, eight studies were included in this meta-analysis. The meta-analysis found a statistically significant difference in favor of exercise in functional ability (P = 0.001), overall quality of life (P = 0.03) and Vo2peak (P = 0.01). The included trials were generally of poor quality and had a risk of bias. However, the results of sensitivity analysis, after omitting studies with high risk of bias, showed no statistically significant difference in functional ability (P = 0.05), overall quality of life (P = 0.12) and Vo2peak (P = 0.13). Finally, no significant difference was found in respiratory function, fatigue, pain, and upper-body and lower-body strength. Conclusions The safety and effectiveness of exercise therapy in ALS patients remains unclear and further high quality RCTs with larger sample size are needed. |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/article/pii/S0031940621000493#! |