| Titre : | Exploring the relationship between meaningful conditioned pain modulation and stress system reactivity in healthy adults following exposure to the cold pressor task (2022) |
| Auteurs : | Michael J. Lukacs ; C.W James Melling ; David M. Walton |
| Type de document : | Article |
| Dans : | Musculoskeletal Science and Practice (Vol. 57, February 2022) |
| Article en page(s) : | 102489 |
| Note générale : | https://doi.org/10.1016/j.msksp.2021.102489 |
| Langues: | Anglais |
| Descripteurs : |
HE Vinci Douleur chronique ; Hormones corticosurrénaliennes ; Marqueurs biologiques ; Mesure de la douleur ; Sensibilité et spécificité |
| Résumé : | Background The sympathetic nervous system (SNS) and hypothalamic-pituitary-adrenal (HPA) axis have been implicated in conditioned pain modulation (CPM). As there has recently been a push to identify meaningful CPM responses based on + 2 SEM of the test stimulus, we sought to evaluate if meaningful CPM had relationships with both SNS and HPA axis reactivity. Methods 50 university-aged healthy participants (25 males, 25 females) underwent evaluation of pressure pain detection threshold (PPDT), conditioned pain modulation (CPM), galvanic skin response (GSR) and salivary cortisol before and after a cold pressor test (CPT). Meaningful CPM was evaluated based on change +2 SEM of baseline PPDT to classify participants as experiencing inhibition of pain, facilitation, or non-response. Results As a group, there were no significant changes in PPDT or salivary cortisol after exposure to noxious cold. GSR was significantly elevated from baseline values during the CPT, and 10 min after (p |
| Disponible en ligne : | Oui |
| En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/article/pii/S2468781221001739 |
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