| Titre : | Which blood cutoff value should be used for vitamin A deficiency in children aged 3–10 years? A systematic review (2021) |
| Auteurs : | Tatiana S. Collese ; Marina M. Norde ; Marcus Vinicius Nascimento-Ferreira ; Hanseul Kim ; Dirce M. Marchioni ; Heráclito B. Carvalho ; Edward Giovannucci |
| Type de document : | Article |
| Dans : | Nutrition reviews (Vol. 79, n° 7, July 2021) |
| Article en page(s) : | p. 777-787 |
| Note générale : | doi:10.1093/nutrit/nuaa133 |
| Langues: | Anglais |
| Descripteurs : |
HE Vinci Diagnostic ; Enfant (6-12 ans) ; Vitamine A |
| Résumé : |
Context:
Blood cutoff values for vitamin A deficiency in children aged 3–10 years have not been addressed in the literature. Objective: To identify blood retinol concentrations for determining severe vitamin A deficiency in children aged 3–10 years. Data Sources: The MEDLINE, Web of Science, Embase, and Scopus databases were searched. Data Extraction: Two reviewers independently extracted article data and assessed quality. Data Analysis: The hierarchical summary receiver operating characteristic models were applied for the diagnostic accuracy meta-analysis. This review is registered at PROSPERO (identifier: CRD42020149367). Results: A total of 15 articles met the eligibility criteria, and 9 were included in the diagnostic accuracy meta-analysis. The summary estimates (95%CI) were: Sensitivity, 0.39 (0.20–0.62); specificity, 0.79 (0.65–0.88); positive likelihood ratio, 1.85 (1.33–2.57); and negative likelihood ratio, 0.77 (0.60–0.99). The area under the curve of the overall analysis was 0.68 (95%CI 0.63–0.72). Conclusions: Blood retinol concentrations have low diagnostic accuracy for severe vitamin A deficiency in children aged 3–10 years. Therefore, there is unclear evidence about the preferable cutoff point for determining severe vitamin A deficiency in children in this age group. |
| Disponible en ligne : | Oui |
| En ligne : | https://login.ezproxy.vinci.be/login?url=https://academic.oup.com/nutritionreviews/article/79/7/777/6056630 |
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