| Titre : | The effect of berberine supplementation on obesity indices: A dose– response meta-analysis and systematic review of randomized controlled trials (2020) |
| Auteurs : | Pan Xiong ; Li Niu ; Sam Talaei ; et al. |
| Type de document : | Article |
| Dans : | Complementary Therapies in Clinical Practice (Vol. 39, May 2020) |
| Article en page(s) : | 8p. |
| Note générale : | https://doi.org/10.1016/j.ctcp.2020.101113 |
| Langues: | Anglais |
| Descripteurs : |
HE Vinci Berbérine ; Indice de masse corporelle ; Méta-analyse ; Obésité ; Poids du corps |
| Résumé : |
Background
and purpose: Clinical studies investigating the effects of berberine supplementation on anthropometric indices in humans have generated inconsistent results. Thus, the objective of this systematic review and meta-analysis was to clarify the effects of berberine supplementation on obesity indices in human subjects. Methods Several online medical databases were systematically searched up to February 2019. All clinical trials exploring the effects of berberine supplementation on indices of obesity were included. The combined weighted mean difference (WMD) of eligible studies was assessed using a random-effects model. We evaluated publication bias by using the Egger's test. Results Overall, 10 studies were included. The combined outcomes suggested a significant influence of berberine administration on body mass index (BMI) (WMD: −0.29 kg/m2, 95% CI: −0.51 to −0.08, p = 0.006) and waist circumference (WC) (WMD: −2.75 cm, 95% CI: −4.88 to −0.62, p = 0.01). However, berberine supplementation yielded no significant decline in body weight (BW) (WMD: −0.11 kg, 95% CI: −0.99 to 0.76, p = 0.79). Following the dose-response evaluation, berberine intake was found to significantly reduce BMI (r = −0.02) and WC (r = −0.72) based on treatment duration. Conclusion The results of the current study support the use of berberine supplementation for the improvement of obesity indices. |
| Disponible en ligne : | Non |
Exemplaires (1)
| Cote | Support | Localisation | Section | Disponibilité |
|---|---|---|---|---|
| Périodique papier | Woluwe | Espace revues | Consultation sur place uniquement Exclu du prêt |
