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Titre : | Effect of saffron supplementation on symptoms of depression and anxiety: a systematic review and meta-analysis (2019) |
Auteurs : | Wolfgang Marx ; Melissa Lane ; Tetyana Rocks ; Anu Ruusunen ; Amy Loughman ; Adrian Lopresti ; Skye Marshall ; Michael Berk ; Felice Jacka ; Olivia M. Dean |
Type de document : | Article |
Dans : | Nutrition reviews (Vol. 77, n° 8, August 2019) |
Article en page(s) : | p.557-571 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Compléments alimentaires ; Dépression ; Inflammation ; Safran ; Santé mentale ; Thérapeutique |
Résumé : |
Context
Saffron (Crocus sativus L.) has gained interest as a potential treatment in psychiatry. Objective This systematic review and meta-analysis sought to investigate the effect of saffron supplementation, as both an adjunctive therapy and monotherapy, on symptoms of depression and anxiety in clinical and general populations compared with pharmacotherapy or placebo. Data sources Using the PRISMA guidelines, a systematic literature review of randomized controlled trials was conducted. Data extraction A meta-analysis was conducted to determine treatment effect. Risk of bias was assessed using the Jadad scale. Results Twenty-three studies were included. Saffron had a large positive effect size when compared with placebo for depressive symptoms (g = 0.99, P Conclusions Saffron could be an effective intervention for symptoms of depression and anxiety; however, due to evidence of publication bias and lack of regional diversity, further trials are required. PROSPERO registration CRD42017070060. |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://academic.oup.com/nutritionreviews/article/77/8/557/5499264 |
Exemplaires (1)
Cote | Support | Localisation | Section | Disponibilité |
---|---|---|---|---|
Nutrition reviews. Vol. 77, n° 8 (August 2019) | Périodique papier | Woluwe | Espace revues | Consultation sur place uniquement Exclu du prêt |