| Titre : | Long-Term Survival After Traumatic Brain Injury Part I: External Validity of Prognostic Models (2015) |
| Auteurs : | Jordan C. Brooks ; Robert M. Shavelle ; David J. Strauss |
| Type de document : | Article |
| Dans : | Archives of Physical Medicine and Rehabilitation (2015/6, 2015) |
| Article en page(s) : | p. 994–999 |
| Langues: | Anglais |
| Descripteurs : |
HE Vinci Etudes de validation ; Mortalité ; Pronostic ; Rééducation et réadaptation ; Survie |
| Mots-clés: | Brain injuries ; Lésions encéphaliques ; Mortality ; Survival ; Prognosis ; Validation studies |
| Résumé : |
Objectives To develop prognostic models for long-term survival in adults with traumatic brain injury (TBI) and to assess their external validity in 2 independent populations. Design Survival analysis. Setting Post-discharge from rehabilitation units and long-term follow-up at regional centers. Participants Two cohorts of long-term survivors of TBI (N=12,481): the Traumatic Brain Injury Model Systems (TBIMS) cohort comprised 7365 persons who were admitted to a TBIMS facility and were assessed at ≥1 years postinjury, and the California Department of Developmental Services (CDDS) cohort comprised 5116 persons who sustained a TBI and received long-term services from the CDDS. Interventions Not applicable. Main Outcome Measures Survival/mortality. Results Older age, male sex, and severity of disability in walking and feeding were significant predictors of increased long-term mortality rates (all P<.05 both databases the cdds model predicted deaths for persons in tbims cohort with an observed-to-expected ratio of .94 confidence interval a total ci regression calibration statistics were satisfactory and models ranked survival times well from shortest to longest c index .78 .76 cdds: .80> Conclusions Long-term survival prognosis in TBI is related to age, sex, and severity of disability. When compared on the basis of these factors, the survival estimates derived from the TBIMS and CDDS cohorts are found to be similar. The close agreement between model predictions and actual mortality rates confirm the external validity of the prognostic models presented herein. |
| Disponible en ligne : | Oui |
| En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/article/pii/S0003999315001094 |
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