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Titre : | Greater Adipose Tissue Distribution and Diminished Spinal Musculoskeletal Density in Adults With Cerebral Palsy (2015) |
Auteurs : | Mark D. Peterson ; Peng Zhang ; Heidi J. Haapala |
Type de document : | Article |
Dans : | Archives of Physical Medicine and Rehabilitation (2015/10, 2015) |
Article en page(s) : | pp. 18281833 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Densite osseuse ; Graisse intra-abdominale ; Paralysie cérébrale ; Rééducation et réadaptation ; Sarcopénie |
Mots-clés: | Adiposity ; Adiposité ; Bone density ; Cerebral palsy ; Intra-abdominal fat ; Sarcopenia |
Résumé : |
Objectives To examine differences in adipose tissue distribution, lumbar vertebral bone mineral density (BMD), and muscle attenuation in adults with and without cerebral palsy (CP), and to determine the associations between morphologic characteristics. Design Cross-sectional, retrospective analyses of archived computed tomography scans. Setting Clinical treatment and rehabilitation center. Participants Adults (N=352) with CP (age, 38.8+14.4y; body mass, 61.3+17.1kg; Gross Motor Function Classification System levels, IV) and a matched cohort of neurotypical adults. Of the 41 adults with CP included in the study, 10 were not matchable because of low body masses. Interventions Not applicable. Main Outcome Measures Computed tomography scans were assessed for visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) areas, psoas major area and attenuation in Hounsfield units (Hu), and cortical and trabecular BMDs. Results Adults with CP had lower cortical (β=−63.41 Hu, P<.001 and trabecular hu p bmds psoas major areas attenuation after controlling for age sex body mass. adults with cp had greater vat sat muscle was significantly correlated cortical bmd whereas negatively associated r2=".13,"> Conclusions Adults with CP had lower BMDs, smaller psoas major area, greater intermuscular adipose tissue, and greater trunk adiposity than neurotypical adults. VAT and cortical BMD were inversely associated. |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/article/pii/S0003999315004876 |