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Titre : | Correlation of Fractional Anisotropy With Motor Recovery in Patients With Stroke After Postacute Rehabilitation (2016) |
Auteurs : | Hongmei Wen ; Mohamad J. Alshikho ; Yao Wang |
Type de document : | Article |
Dans : | Archives of Physical Medicine and Rehabilitation (2016/9, 2016) |
Article en page(s) : | pp. 14871495 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Accident vasculaire cérébral (AVC) ; Imagerie par tenseur de diffusion ; Rééducation et réadaptation |
Mots-clés: | Diffusion tensor imaging ; Stroke |
Résumé : |
Objective To investigate the relation between fractional anisotropy (FA), a suggested biomarker for tissue integrity, and motor recovery in patients with stroke after postacute rehabilitation. Design Retrospective study. Setting Acute rehabilitation hospital. Participants Subjects (N=43) diagnosed with ischemic stroke (n=28) and hemorrhagic stroke (n=15). The average age for subjects was 68+14 years. Interventions Magnetic resonance imaging and diffusion tensor imaging were conducted on all patients. Main Outcome Measures The admission and discharge motor subscores of the FIM were obtained from medical records, and relative gain was calculated using the Montebello Rehabilitation Factor Score (MRFS). K-means cluster analysis (K=3) using both the MRFS and the gain of the FIM motor subscore (ΔFIM) was performed. Analysis of variance was used to determine the difference in FA among the clusters. Spearman analysis was conducted to examine the relation between FA, ΔFIM, and MRFS in each cluster. Results FA was significantly higher in the clusters of good and moderate recovery in the corticospinal tract (CST), peduncle, and posterior limb of the internal capsule bilaterally (all P<.05 compared with the poor recovery group. significant positive correlations were observed in multiple regions along cst between fa and mrfs clusters of good moderate but not> Conclusions Our results showed an association between FA values within the corticospinal tract and motor recovery in patients with stroke undergoing postacute rehabilitation. This finding may help to identify novel targets for new interventions to promote stroke recovery. |
Disponible en ligne : | Oui |
En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/science/article/pii/S0003999316301460 |