| Titre : | Changes in Health Status Among Aging Survivors of Pediatric Upper and Lower Extremity Sarcoma: A Report From the Childhood Cancer Survivor Study (2013) |
| Auteurs : | Neyssa Marina ; Mélissa Hudson ; Kendra Jones ; et al. |
| Type de document : | Article |
| Dans : | Archives of Physical Medicine and Rehabilitation (2013/6, 2013) |
| Article en page(s) : | pp. 1062-1073 |
| Langues: | Anglais |
| Descripteurs : |
HE Vinci Membre inférieur ; Membre supérieur ; Rééducation et réadaptation ; Survivants ; Tumeurs |
| Mots-clés: | Lower extremity ; Neoplasms ; Sarcoma ; Sarcomes ; Survivors ; Upper extremity |
| Résumé : |
Objective To evaluate health status and participation restrictions in survivors of childhood extremity sarcomas. Design Members of the Childhood Cancer Survivor Study cohort with extremity sarcomas who completed questionnaires in 1995, 2003, or 2007 were included. Setting Cohort study of survivors of extremity sarcomas. Participants Childhood extremity sarcoma survivors (N=1094; median age at diagnosis, 13y (range, 0–20y); current age, 33y (range, 10–53y); 49% male; 87.5% white; 75% had lower extremity tumors) who received their diagnosis and treatment between 1970 and 1986. Interventions Not applicable. Main Outcome Measures Prevalence rates for poor health status in 6 domains and 5 suboptimal social participation categories were compared by tumor location and treatment exposure with generalized estimating equations adjusted for demographic/personal factors and time/age. Results In adjusted models, when compared with upper extremity survivors, lower extremity survivors had an increased risk of activity limitations but a lower risk of not completing college. Compared with those who did not have surgery, those with limb-sparing (LS) and upper extremity amputations (UEAs) were 1.6 times more likely to report functional impairment, while those with an above-the-knee amputation (AKA) were 1.9 times more likely to report functional impairment. Survivors treated with LS were 1.5 times more likely to report activity limitations. Survivors undergoing LS were more likely to report inactivity, incomes Conclusions Treatment of lower extremity sarcomas is associated with a 50% increased risk for activity limitations; upper extremity survivors are at a 10% higher risk for not completing college. The type of local control influences health status and participation restrictions. Both of these outcomes decline with age. |
| Disponible en ligne : | Oui |
| En ligne : | https://login.ezproxy.vinci.be/login?url=https://www.sciencedirect.com/journal/archives-of-physical-medicine-and-rehabilitation |
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