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Titre : | Responsiveness of the Motor Function Measure in Neuromuscular Diseases (2012) |
Auteurs : | Carole Vuillerot ; Christine Payan ; Françoise Girardot ; et al. |
Type de document : | Article |
Dans : | Archives of Physical Medicine and Rehabilitation (2012/12, 2012) |
Article en page(s) : | pp. 2251-2256 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Activités de la vie quotidienne ; Évaluation de résultat (soins) ; Rééducation et réadaptation |
Mots-clés: | évaluation de l'incapacité ; myopathie de Duchenne ; maladies neuromusculaires |
Résumé : |
"Objectives To study the responsiveness (sensitivity to change) of the Motor Function Measure (MFM) in detecting change in neuromuscular disease patients with the intent of using this measure in future clinical trials. Design Prospective cohort observational study. Setting Inpatient and outpatient facilities for follow-up and treatment of neuromuscular diseases. Participants Patients (N=152) with various neuromuscular diseases aged 6 to 60 years. Interventions Not applicable. Main Outcome Measure(s) We used the MFM total score and its 3 subscores on 2 measurements grossly 1 year apart. The physicians and the patients (or proxy) were asked to provide their perceived change in functional status since the first MFM. These changes were expressed in 3 outcomes: deterioration, stability, or improvement. Results The overall 12-month-standardized mean change of the total score mean + SD annual total score change was −2.4+5.5 points (P<.001 with patients duchenne muscular dystrophy presenting the most significant change p in reporting deterioration was significantly larger than that of those stability or improvement vs and points respectively total score changes were greater physician-rated deteriorated versus stable mean differences scores being> Conclusions The MFM showed a good responsiveness, especially in patients with DMD and agreements with patients' and physicians' perceived change. Confirming this responsiveness requires larger age groups of patients with DMD and other neuromuscular diseases as well as disease-specific interexamination delays." |
Disponible en ligne : | Oui |
En ligne : | http://www.archives-pmr.org/article/S0003-9993(12)00404-2/abstract |