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Titre : | Lung Volume Recruitment Slows Pulmonary Function Decline in Duchenne Muscular Dystrophy (2012) |
Auteurs : | Douglas McKim ; Sherri Katz ; Nicholas Barrowman ; et al. |
Type de document : | Article |
Dans : | Archives of Physical Medicine and Rehabilitation (2012/7, 2012) |
Article en page(s) : | pp. 1117-1122 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Rééducation et réadaptation ; Tests de la fonction respiratoire |
Mots-clés: | Muscular dystrophy ; Duchenne ; Respiratory function tests ; Vital capacity ; Myopathie de Duchenne ; Capacité vitale |
Résumé : |
Objective To evaluate the long-term effect on measures of forced vital capacity (FVC) before and after the introduction of regular lung volume recruitment (LVR) maneuvers (breath-stacking) in individuals with Duchenne muscular dystrophy (DMD). Design Retrospective cohort study of pulmonary function data, including FVC, cough peak flow (CPF), maximum inspiratory pressure (MIP), and maximum expiratory pressure (MEP). Data were collected for 33 months prior to and 45 months after LVR introduction. Setting Ambulatory care in a tertiary level regional rehabilitation center in Canada. Participants All individuals (N=22) with DMD (mean age + SD, 19.6+2.4y), who were prescribed LVR and reported adherence with therapy. Interventions Introduction of regular LVR (breath-stacking); 3 to 5 maximal lung inflations (maximum insufflation capacity [MIC]) using a hand-held resuscitation bag and mouthpiece, twice daily. Main Outcome Measures Measures included the rate of decline of FVC in percent-predicted, before and after the introduction of regular LVR. Changes in maximum pressures (MIP, MEP), MIC, and cough peak flows were also measured. Results At LVR initiation, FVC was 21.8+16.9 percent-predicted, and cough peak flows were Conclusions The rate of FVC decline in DMD patients improves dramatically with initiation of regular LVR. |
Disponible en ligne : | Oui |
En ligne : | http://www.archives-pmr.org/article/S0003-9993%2812%2900162-1/abstract |