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Titre : | Late effects and quality of life after chemo-radiation for the treatment of anal cancer (2015) |
Auteurs : | Gillian Knowles, Auteur ; Rachel Haigh, Auteur ; Catriona Mclean, Auteur |
Type de document : | Article |
Dans : | European Journal of Oncology Nursing (Vol. 19, n° 5, October 2015) |
Article en page(s) : | p. 479-485 |
Langues: | Anglais |
Descripteurs : |
HE Vinci Ceinture pelvienne ; Chimiothérapie ; Qualité de vie ; Radiothérapie |
Mots-clés: | Cancer de l'anus |
Résumé : |
Purpose
The aim of this study was to evaluate the late effects and quality of life of patients following chemo-radiation treatment for anal cancer. Methods All surviving anal cancer patients treated within NHS Lothian between 1990 and 2007 were invited to participate. Data were collected using the EORTC QLQ-C30, the EORTC QLQ-CR38 and the Memorial Sloan-Kettering Cancer Centre Bowel Function Instrument (MSKCC). Results Overall response rate was 46% (n = 42); mean age 54.7 years and with a median time interval of 63.8 months between treatment and completion of the questionnaires. Thirty-five percent of the participants were rarely or never able to wait 15 min to get to the toilet; 50% were rarely or never able to control the passage of gas; 35% limited the types of solid foods they eat; 22% had leakage of stool during the day; 39% required to use a protective pad and 29% altered their daily activities because of bowel function always or most of the time. Seventeen percent of patients reported financial difficulties (quite a bit and very much). Both men and women reported high symptomology for sexual problems with a median score of 83.3 (50.0. 100.0). Conclusion This study has shown that in a sub-set of patients treated with chemo-radiation for anal cancer, persistent treatment related issues are reported at a medium time interval of 5.3 years. Further work is now required to understand the impact of symptoms on day-to-day life and the challenges that people face in managing these inter-related and complex problems. |
Disponible en ligne : | Non |
Exemplaires (1)
Cote | Support | Localisation | Section | Disponibilité |
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REV | Périodique papier | Woluwe | Espace revues | Consultation sur place uniquement Exclu du prêt |