|
[article] | Titre : |
Associations between vitamin D status in pregnancy and offspring neurodevelopment: a systematic literature review |
| Type de document : |
texte imprimé |
| Auteurs : |
Janet Janbek ; Ina O. Specht ; Berit L. Heitmann |
| Année de publication : |
2019 |
| Article en page(s) : |
330-349 |
| Langues : |
Anglais (eng) |
| Descripteurs : |
HE Vinci
Cerveau ; Foetus ; Grossesse ; Maladies de carence ; Vitamine D
|
| Résumé : |
Abstract
Context
Vitamin D plays an important role in the development of the brain, which is one of the earliest fetal organs to develop. Results from epidemiological studies investigating associations between maternal levels of vitamin D during pregnancy and offspring neurodevelopment are mixed and inconclusive.
Objective
This systematic review of studies that examined vitamin D levels in pregnancy and offspring neurodevelopment used 3 specific domains—timing of exposure during pregnancy trimesters, neurodevelopmental outcomes, and offspring age at assessment of outcomes—to determine whether vitamin D status in pregnancy is associated with offspring neurodevelopment.
Data Sources
A search of the Embase, PsychInfo, Scopus, and The Cochrane Library databases in September 2017 and February 2018 identified 844 articles, of which 46 were retrieved for full-text assessment.
Study Selection
Eligibility criteria were used to select studies. All authors examined the studies, and consensus was reached through discussion. Results were divided according to the 3 domains.
Data Extraction
Authors examined the studies independently, and data from eligible studies were extracted using a modified version of the Cochrane data collection form. Using the modified Downs and Black checklist, 2 authors assessed the quality of the studies independently and were blinded to each other’s assessment. Consensus was reached upon discussion and with the involvement of the third author.
Results
Fifteen observational studies were included. Vitamin D in pregnancy was associated with offspring language and motor skills in young children. Associations persisted into adolescence, and results were not dependent on the timing of vitamin D exposure during pregnancy. No supplementation studies were identified.
Conclusions
There is some evidence that low vitamin D status in pregnancy is associated with offspring language and motor development, particularly in young children. |
| En ligne : |
https://academic.oup.com/nutritionreviews/article/77/5/330/5365312 |
in Nutrition reviews > Vol. 77, n° 5 (2019) . - 330-349
[article] Associations between vitamin D status in pregnancy and offspring neurodevelopment: a systematic literature review [texte imprimé] / Janet Janbek ; Ina O. Specht ; Berit L. Heitmann . - 2019 . - 330-349. Langues : Anglais ( eng) in Nutrition reviews > Vol. 77, n° 5 (2019) . - 330-349 | Descripteurs : |
HE Vinci
Cerveau ; Foetus ; Grossesse ; Maladies de carence ; Vitamine D
|
| Résumé : |
Abstract
Context
Vitamin D plays an important role in the development of the brain, which is one of the earliest fetal organs to develop. Results from epidemiological studies investigating associations between maternal levels of vitamin D during pregnancy and offspring neurodevelopment are mixed and inconclusive.
Objective
This systematic review of studies that examined vitamin D levels in pregnancy and offspring neurodevelopment used 3 specific domains—timing of exposure during pregnancy trimesters, neurodevelopmental outcomes, and offspring age at assessment of outcomes—to determine whether vitamin D status in pregnancy is associated with offspring neurodevelopment.
Data Sources
A search of the Embase, PsychInfo, Scopus, and The Cochrane Library databases in September 2017 and February 2018 identified 844 articles, of which 46 were retrieved for full-text assessment.
Study Selection
Eligibility criteria were used to select studies. All authors examined the studies, and consensus was reached through discussion. Results were divided according to the 3 domains.
Data Extraction
Authors examined the studies independently, and data from eligible studies were extracted using a modified version of the Cochrane data collection form. Using the modified Downs and Black checklist, 2 authors assessed the quality of the studies independently and were blinded to each other’s assessment. Consensus was reached upon discussion and with the involvement of the third author.
Results
Fifteen observational studies were included. Vitamin D in pregnancy was associated with offspring language and motor skills in young children. Associations persisted into adolescence, and results were not dependent on the timing of vitamin D exposure during pregnancy. No supplementation studies were identified.
Conclusions
There is some evidence that low vitamin D status in pregnancy is associated with offspring language and motor development, particularly in young children. |
| En ligne : |
https://academic.oup.com/nutritionreviews/article/77/5/330/5365312 |
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